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[Bilateral phrenic nerve paralysis, dysautonomia and restrictive cardiomyopathy in a case of POEMS syndrome].
Rev Neurol (Paris)
July 2002
Service de neurologie D, Hôpital Roger Salengro, 59037 Lille.
We report a case of POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, M protein and Skin changes) with unusual clinical features. A 62-year-old woman presented a severe polyneuropathy with dysphonia and vegetative symptoms, including bradycardia and sphincterial disorders. The clinical examination showed facial hyperpigmentation, cachexia, anasarca and splenomegaly.
View Article and Find Full Text PDFPOEMS syndrome: definitions and long-term outcome.
Blood
April 2003
Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.
The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) remains poorly understood. Ambiguity exists over the features necessary to establish the diagnosis, treatment efficacy, and prognosis. We identified 99 patients with POEMS syndrome.
View Article and Find Full Text PDFCardiomyopathy in a case of Crow-Fukase syndrome.
Jpn Heart J
November 1997
Second Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
Crow-Fukase syndrome or POEMS syndrome is a variant of plasma cell dyscrasia that is characterized by polyneuropathy, organomegaly, endocrinopathy, the presence of M-protein in serum, and dermatological changes. A 60-year-old man presented with features of Crow-Fukase syndrome, such as the presence of M-protein in serum, dermatological changes, and osteosclerotic changes, but did not have polyneuropathy. To our knowledge, this is the first case of Crow-Fukase syndrome in which the presence of hypertrophic cardiomyopathy has been confirmed by a left endomyocardial biopsy.
View Article and Find Full Text PDFPOEMS syndrome presenting with cardiomegaly and cardiomyopathy.
J Intern Med
April 1992
Department of Medicine, Evaston Hospital, McGaw Medical Center of Northwestern University, Illinois.
A rare association of multisystemic manifestations with plasma cell dyscrasia has been termed POEMS syndrome, which includes polyneuropathy, organomegaly, endocrinopathy. M-protein, and skin changes. From literature reports, organomegaly consists of hepatosplenomegaly and/or lymphadenopathy.
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