Background: Second malignancies are a well recognized complication of radiation therapy.

Methods: We performed a computer search of the literature using the Medline Database for Pericardial Tumors and Post-Irradiation Sarcomas.

Results: The case history of a patient who developed a radiation-induced pericardial angiosarcoma is described. We present a detailed review of pericardial sarcomas.

Conclusions: We believe this to be the first report of a radiation-induced pericardial sarcoma. The importance of continued long-term observation for patients who receive mediastinal irradiation is stressed.

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http://dx.doi.org/10.1002/(SICI)1097-0142(19960815)78:4<912::AID-CNCR31>3.0.CO;2-WDOI Listing

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