Clinical (neurological), neurophysiological (EEG) and psychological examinations were carried out in 3 children with general speech defects. These children represented 3 main groups with speech disturbances: with speech defects which may be logopedically corrected, with speech defect and intact intellectual ability, with considerable disturbances of speech and cognitive functions. The peculiarities of cognitive disturbances were determined in each group. They were manifested in the form of alterations either of basic EEG or of EEG response to different stimuli as well as in psychological profile structure.
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J Clin Med
December 2024
Department of Maxillofacial Surgery, University of Siena, 53100 Siena, Italy.
: Currently, there is a lack of a comprehensive classification system for soft-palate defects that provides synthetic information to guide functional reconstructive treatment. Our awareness, shaped by extensive experience, of the superiority of myomucosal flaps to fasciocutaneous flaps in functional palate reconstruction has driven us to introduce a new defect-based classification system and propose a new algorithm for reconstructing soft-palate defects using buccinator myomucosal flaps. : Soft-palate defects were classified into five classes.
View Article and Find Full Text PDFBioengineering (Basel)
December 2024
Department of Communication Sciences and Disorders, University of Iowa, Iowa City, IA 52242, USA.
Room reverberation can affect oral/aural communication and is especially critical in computer analysis of voice. High levels of reverberation can distort voice recordings, impacting the accuracy of quantifying voice production quality and vocal health evaluations. This study quantifies the impact of additive simulated reverberation on otherwise clean voice recordings as reflected in voice metrics commonly used for voice quality evaluation.
View Article and Find Full Text PDFChildren (Basel)
December 2024
School of Medical Sciences, State University of Campinas, Campinas 13083-887, Brazil.
Introduction: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a new member of the coronavirus family. While respiratory transmission is the main route, concerns have arisen regarding possible vertical transmission, which refers to the transmission of the virus from mother to fetus through the dissemination of viral particles in the amniotic fluid. Fetal viral infection via the placenta can affect the formation of the auditory system and lead to congenital hearing disorders.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Department of Speech Therapy, School of Health Sciences, University of Ioannina, 45500 Ioannina, Greece.
A specific deletion on the short arm of chromosome 5 (5p) is the hallmark of the rare genetic syndrome called Cri du Chat Syndrome (CdCS). It causes severe difficulty with swallowing, speech, motor skills, and cognitive deficiencies. These arise from characteristic laryngeal abnormalities and oral-motor dysfunctions.
View Article and Find Full Text PDFEur J Paediatr Neurol
January 2025
Department of Pediatric Neurology, University Children's Hospital and Medical Faculty, Justus Liebig University of Giessen, Giessen, Germany.
Background: CACNA1A-related disorders are rare and progressive; to date, there is no approved treatment. Trials with N-acetyl-leucine (NAL) demonstrated efficacy in disorders featuring ataxia, cognitive impairment, and epilepsy. Accordingly, we hypothesized that NAL may be effective in CACNA1A-associated disorders.
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