The clinical case of a 45-years old patient with previous diagnosis of alcoholic cirrhosis who was admitted to study the appearance of a picture consisting in erythematoviolescent lesions in the lower limbs and advanced renal failure is presented. Anatomopathologic study of the cutaneous lesions suggested the diagnosis of leukocytoclastic vasculitis. This fact was of special clinical interest on having taken into consideration the cytologic demonstration of hepatocarcinoma superimposed to the established chronic liver disease of the patient. The rarity of leukocytoclastic vasculitis as the initial clinical manifestation of a hepatocarcinoma versus the most common forms of presentation is herein discussed.
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J Clin Med
January 2025
Department of Pulmonary Medicine, European Hospital Georges Pompidou, 75015 Paris, France.
: Cryoglobulinemia (CG) syndrome is a heterogeneous condition characterized by the presence of cryoglobulins in serum, often leading to vasculitis with protean clinical manifestations. Understanding the presentation of cryoglobulinemia-related symptoms based on cryoprecipitate levels, GC type, and severity at diagnosis is essential for effective management. Hence, this study aimed to provide a comprehensive analysis of patients with positive cryoglobulin detection to investigate these aspects.
View Article and Find Full Text PDFRheumatology (Oxford)
January 2025
Department of internal medicine, CHU Cochin, AP-HP, Paris Cité University, Paris, F-75006, France.
Objectives: Urticarial vasculitis (UV) is characterized by atypical urticarial lesions and leukocytoclastic vasculitis, sometimes with extracutaneous manifestations. First-line treatment is based on colchicine, hydroxychloroquine, dapsone or low-dose glucocorticoids. In refractory forms, the use of biologics has been anecdotally described as potentially effective.
View Article and Find Full Text PDFClin Exp Dermatol
January 2025
Dermatology department, Dupuytren 2 University Hospital, Limoges, France.
S D Med
October 2024
Transitional Year Residency Program, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
IgA vasculitis is a small vessel vasculitis and while it represents the most common form of vasculitis in pediatric populations, it is rare in adults. This manuscript describes a case of skin limited IgA vasculitis in an 84-yearold Caucasian female. The patient presented for bilateral lower extremity rash that occurred roughly one month following a viral upper respiratory illness.
View Article and Find Full Text PDFClin Rheumatol
January 2025
Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8524, Japan.
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