One hundred and fifty patients with trigeminal neuralgia were treated by percutaneous compression of the Gasserian ganglion (PCGG) during the last 8 years. The technique is the one described by Mullan with the balloon inflated during 6 minutes with 0,7 cc of contrast medium. Over a follow-up period ranging from 6 months to 8 years with an average of 4 years, one hundred and four patients (69,3%) have remained painfree. Postoperative complications included dysaesthesias in 16 patients (moderate in 15), hypo-aesthesia in 140 (moderate in 138), hypo-acousia and otalgia in ten, and masticatory weakness also in ten. The recurrence rate was 30%. The main advantages of the procedure are exceptionally severe dysaesthesias (one case), the rarity of corneal complications (4 cases), the short hospital stay (three days on average). Its disadvantage is the need for a general anaesthetic. This study shows that percutaneous compression is efficacious and technically easy.
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http://dx.doi.org/10.1007/BF01411438 | DOI Listing |
Int Cancer Conf J
January 2025
Department of Respiratory Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa Japan.
Osimertinib has emerged as the standard first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mutations, offering improved tolerability and demonstrating superior efficacy against brain metastases in comparison with other tyrosine kinase inhibitors. The Meckel's cave is a dural recess in the posteromedial part of the middle cranial fossa that acts as a conduit for the trigeminal nerve between the anterior pontine cisterna and the cavernous sinus, and houses the Gasserian ganglion and proximal radicle of the trigeminal nerve. Trigeminal neuropathy, characterized by numbness and dysesthesia of the skin and mucous membranes of the face, poses diagnostic challenges and often requires differentiation from conditions, such as compression neuropathy, inflammation, and drug-induced reactions.
View Article and Find Full Text PDFPain Physician
September 2024
Fuzhou University Affiliated Provincial Hospital, Fuzhou, China; Department of Ophthalmology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China.
Background: The degree of cervical extension required during percutaneous balloon compression (PBC) of the Gasserian ganglion for trigeminal neuralgia (TN) varies among patients, but the traditional operating tables often fail to fulfil each patient's individual requirements.
Objective: This study aimed to compare the clinical efficacy of an extended operating table to that of a traditional operating table in C-arm-guided PBC of the Gasserian ganglion for TN.
Study Design: This is a consecutively prospective comparative study.
Pain Physician
July 2024
--Department of Pain Medicine, The Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang province, P.R. China.
Background: The classic percutaneous balloon compression (PBC) technique is used to complete an operation under the guidance of C-arm radiography under general anesthesia, making communication with patients during the operation impossible. It is not accurate or objective to predict the classic technique's curative effect solely by determining whether the projection of the x-ray lateral image of the filled balloon is pear-shaped.
Objectives: This study aimed to upgrade classic PBC to awake computed tomography (CT)-guided PBC technology under conscious local anesthesia and analgesia monitoring.
Acta Neurochir (Wien)
July 2024
Department of Neurosurgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Background: Surgical treatment for trigeminal neuralgia includes percutaneous techniques, including balloon compression, first described in 1983 by Mullan and Lichtor (J Neurosurg 59(6):1007-1012, 6).
Method: Here we present a safe and simple navigation-assisted percutaneous technique for balloon compression, which can also be used for glycerol injection.
Conclusion: The navigation-assisted percutaneous technique for balloon compression for trigeminal neuralgia is a quick and safe treatment for patients not candidates for microvascular decompression.
Neurol Res
August 2024
Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Background: As a simple and safe alternative intervention, percutaneous balloon compression (PBC) has been gradually adopted by a growing number of neurosurgeons to treat trigeminal neuralgia. A pear-shaped opacity observed fluoroscopically, which indicates full suffusion of Meckel's cave conducting sufficient pressure against Gasserian ganglion, is believed to be the key to its success. Sometimes, a bitten pear may appear due to bubbles in the balloon but is usually ignored.
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