We investigated the short-term effects of an intrathecal bolus injection of baclofen on central pain due to stroke or spinal cord injury. Pain relief was obtained in 64% of the patients. The effects developed 1-2 hours after the injection and continued for 10-24 hours. Both spinal segmental and supraspinal mechanisms may be involved in the production of baclofen-analgesia.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-7091-9419-5_30DOI Listing

Publication Analysis

Top Keywords

approach control
4
control central
4
central deafferentation
4
deafferentation pain--spinal
4
pain--spinal intrathecal
4
intrathecal baclofen
4
baclofen investigated
4
investigated short-term
4
short-term effects
4
effects intrathecal
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!