This retrospective cephalometric study examined the facial changes brought about by treatment in 62 Class II division 1 children, using tensor analysis. Thirty-two children were treated with Fränkel appliances, whilst the remaining thirty received premolar extractions, headgear, and conventional Edgewise mechanics. Each child was matched for age and sex with an untreated individual in whom the occlusion was deemed satisfactory and the treatment changes were compared with those expected during normal development. Results indicated that vertical facial development predominated in both treated groups: this exceeded the increase expected in an untreated population . The Fränkel group exhibited the greater gain in lower face height, with changes confined almost entirely to the mandible. Effective mandibular position improved but there was no increase in body length. The incisors were more favourably positioned within the face with similar improvements in the soft tissues. Thus, although facial balance was better following a non-extraction Fränkel approach, control of the vertical dimension was inadequate. The fixed appliance group exhibited a smaller increase in lower facial height and no favourable mandibular development: maxillary retraction was the most striking skeletal alteration. By removing the traditional, fixed, superimpositional framework of the cranial base, tensor analysis highlights vertical and mandibular changes not easily detected by conventional cephalometry.
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http://dx.doi.org/10.1093/ejo/18.1.41 | DOI Listing |
Eur Radiol
January 2025
Department of Radiology, Affiliated Children's Hospital of Jiangnan University, Wuxi, China.
Objectives: To assess glymphatic function and white matter integrity in children with autism spectrum disorder (ASD) using multi-parametric MRI, combined with machine learning to evaluate ASD detection performance.
Materials And Methods: This retrospective study collected data from 110 children with ASD (80 exploratory, 43 validation) and 68 typically developing children (50 exploratory, 18 validation) from two centers. The automated diffusion tensor imaging along the perivascular space (aDTI-ALPS), fractional anisotropy (FA), cerebrospinal fluid volume, and perivascular space (PVS) volume indices were extracted from DTI, three-dimensional T1-weighted, and T2-weighted images.
Sci Rep
January 2025
Institute for X-ray Physics, Georg-August University Göttingen, Friedrich-Hund-Platz 1, 37077, Göttingen, Germany.
Imaging the entire cardiomyocyte network in entire small animal hearts at single cell resolution is a formidable challenge. Optical microscopy provides sufficient contrast and resolution in 2d, however fails to deliver non-destructive 3d reconstructions with isotropic resolution. It requires several invasive preparation steps, which introduce structural artefacts, namely dehydration, physical slicing and staining, or for the case of light sheet microscopy also clearing of the tissue.
View Article and Find Full Text PDFJ Chromatogr A
January 2025
Dipartimento di Ingegneria Chimica Materiali Ambiente, Sapienza Università di Roma, Italy. Electronic address:
The exact moment method for the determination of the dispersion tensor in retentive porous media has been adopted to compute the dispersion coefficients, the plate height curves and the kinetic performance factors of eight different 3D printable stationary phases based on triply periodic minimal surfaces (TPMS). The two cases in which the stationary phase is impermeable (hydrodynamic dispersion) or superficially retentive have been analyzed in detail. The Carman-Kozeny relationship between permeability K, hydraulic diameter d and hydrodynamic tortuosity τ holds true for all the geometries investigated with a unique shape coefficient K.
View Article and Find Full Text PDFEur Radiol
January 2025
Department of Radiology, The First Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
Objectives: To investigate glymphatic function in idiopathic normal pressure hydrocephalus (iNPH) using the diffusion tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the associations of ALPS index with ventriculomegaly and white matter hyperintensities (WMH).
Materials And Methods: This study included 41 patients with iNPH and 40 age- and sex-matched normal controls (NCs). All participants underwent brain MRI.
Hum Brain Mapp
February 2025
Department of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Apathy is a common neuropsychiatric symptom following stroke, characterized by reduced goal-directed behavior. The reward decision network (RDN), which plays a crucial role in regulating goal-directed behaviors, is closely associated with apathy. However, the relationship between poststroke apathy (PSA) and RDN dysfunction remains unclear due to apathy heterogeneity, the confounding effect of depression and individual variability in lesion impacts.
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