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Acute and Subchronic Toxicity of 6PPD-Quinone to Early Life Stage Lake Trout ().
Environ Sci Technol
January 2025
Toxicology Centre, University of Saskatchewan, Saskatoon S7N 5B3, Canada.
-(1,3-Dimethylbutyl)-'-phenyl--phenylenediamine-quinone (6PPD-Q) is a rubber-tire derivative which leaches into surface waters from roadway runoff, from tire particles and has been identified as a possible driver of urban runoff mortality syndrome in coho salmon. Sensitivity to this toxicant is highly variable across fish species and life stages. With environmental concentrations meeting or exceeding toxicity thresholds in sensitive fishes, the potential for ecologically relevant effects is significant.
View Article and Find Full Text PDFPrognosis of Cardiovascular Conditions Noninvasively Using Printable Elastomeric Electronic Skin.
Adv Healthc Mater
January 2025
Rubber Technology Centre, Indian Institute of Technology Kharagpur, Kharagpur, 721302, India.
Lack of timely prognosis of cardiovascular condition (CVC) is resulting in increased mortality across the globe. Currently, available techniques are confined to medical facilities and need the intervention of specialists. Frequently, this impedes timely treatment, driven by socioeconomic factors.
View Article and Find Full Text PDFA cross-sectional study of poisoning deaths by rubber latex processing acid in Tripura, India.
Med J Armed Forces India
December 2024
Associate Professor (Forensic Medicine), Agartala Government Medical College, Tripura, India.
Background: Rubber latex processing acid poisoning is a frequently encountered phenomenon in Tripura. Formic acid is the preferred choice for coagulating rubber latex in rubber sheet manufacturing units. The objective of this study aimed to assess the epidemiological profile of poisoning deaths by rubber processing acid and to record their autopsy findings.
View Article and Find Full Text PDFStructurally Selective Ozonolysis of -Phenylenediamines and Toxicity in Coho Salmon and Rainbow Trout.
Environ Sci Technol
December 2024
Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.
The tire-rubber-derived ozonation product of -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine (6PPD), -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine-quinone (6PPD-Q), was recently discovered to cause acute mortality in coho salmon (). -Phenylenediamines (PPDs) with variable side chains distinct from 6PPD have been identified as potential replacement antioxidants, but their toxicities remain unclear under environmentally relevant ozone conditions. We herein tested the multiphase gas-surface ozone reactivity of four select PPDs [6PPD, -isopropyl-'-phenyl--phenylenediamine (IPPD), ,'-diphenyl--phenylenediamine (DPPD), and -phenyl-'-cyclohexyl--phenylenediamine (CPPD)] and evaluated the toxicity of their reaction mixtures in coho salmon, rainbow trout (), and fathead minnow ().
View Article and Find Full Text PDFBladder cancer: a retrospective audit at a single radiation oncology unit of an academic hospital in Johannesburg, South Africa.
J Egypt Natl Canc Inst
November 2024
University of the Witwatersrand, Faculty of Health Sciences, School of Clinical Medicine, Department of Radiation Sciences, Division of Radiation Oncology, University of the Witwatersrand, Faculty of Health Sciences, School of Clinical Medicine, Department of Radiation Sciences, Division of Radiation Oncology, Johannesburg, South Africa.
Background: Bladder cancer (BCa) is one of the most common urological cancers and remains a leading cause of cancer-related mortality worldwide. Bladder cancer is associated with a range of risk factors, with smoking being one of the most significant contributors. In addition to smoking, exposure to certain chemicals, particularly aromatic amines found in industries such as dye, rubber, leather, and textiles, also increases the risk of bladder cancer.
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