The authors replicated and extended two former studies on Axis I and II comorbidity and childhood trauma histories in 106 patients admitted to a chemical dependency treatment unit. Sixty-nine subjects reported a history of physical and/or sexual abuse during childhood and 26.4% met criteria for posttraumaic stress disorder. Patients who reported a history of childhood abuse showed more symptoms of depression, dissociation, and borderline personality disorder than those who denied childhood trauma. Dissociative disorders, mood and anxiety disorders, personality disorders, and histories of childhood trauma appear to be common in chemical dependency subjects, and should be inquired about routinely.
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Sci Rep
January 2025
Laboratory of Integrative Neuroscience (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil.
Maternal adverse childhood experiences (ACEs) are linked to negative health and developmental outcomes in offspring. However, whether maternal ACEs influence infant weight gain in the first months of life, and if this effect differs by infant sex, remains unclear. This study included 352 full-term newborns from low-risk pregnancies and their mothers in low-income settings in Brazil.
View Article and Find Full Text PDFPsychoneuroendocrinology
January 2025
School of Sport, Exercise and Health Sciences, Loughborough University, United Kingdom.
Dysregulation of hypothalamic-pituitary-adrenal axis (HPA axis) and of the autonomic nervous system may link stress throughout the life course with poorer health. This study aims to investigate whether multiple adverse childhood experiences have a long-term impact on markers of these systems - cortisol secretion and heart rate variability - in adulthood. Data were from the Whitehall II cohort study.
View Article and Find Full Text PDFSoc Sci Med
December 2024
Thomas Jefferson University College of Population Health, 130 S. 9th Street, Suite 100. Philadelphia, PA, 19107, USA.
In this paper, we apply a measurement science perspective to explore both the epidemiologic and psychometric frameworks for the conceptualization, operationalization and assessment of self-reported adverse childhood experiences (srACEs). The epidemiologic paradigm suggests that srACEs are 'exposures', while the psychometric paradigm views responses on srACEs instrumentation as 'indicators'. It is the central premise of this paper that srACEs cannot be both exposures and indicators of scales.
View Article and Find Full Text PDFBreast
January 2025
Oncology Division, Rambam Health Care Campus, HaAliya HaShniya St 8, Haifa, 3109601, Israel; Bruce Rappaport Faculty of Medicine, Technion Israeli Institute of Technology, Efron St 1, Haifa, 3525433, Israel. Electronic address:
Background: Pain and subjective cognitive decline (SCD) are common sequala of breast cancer (BC) treatment. Adverse childhood experiences (ACEs) are associated with pain and adverse health outcomes in noncancer population. Sense of coherence (SOC) reflects the disposition that life is manageable and predictable.
View Article and Find Full Text PDFAIDS Care
January 2025
South African Medical Research Council / Stellenbosch University Genomics of Brain Disorders Research Unit, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
HIV and the consequences of HIV-associated neurocognitive disorders (HAND) disproportionally affect South African women. Longitudinal neurocognitive data on women with HIV are limited. We tracked longitudinal neurocognitive profiles of South African women with HIV (baseline = 140) compared to women without HIV (baseline = 156).
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