Gastric mucosa of obese patients with duodenal ulcer was investigated by means of light and electron microscopy and morphometrically. The comparison of the morphological findings and data on gastric secretion shows that overall volume of functional structures of the parietal and peptic cells providing secretion is smaller in duodenal ulcer patients with obesity than in non-obese patients. Elevated gastric secretion in these patients is maintained by hyperfunction of the corresponding structures.
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