The certificates of death of 14 deceased patients with Laurence-Moon-Bardet-Biedl (LMBB) syndrome, in which retinal dystrophy is dominant feature, were review. Death occurred at a considerably younger age than in the general population. Renal disease was noted as primary or contributing cause of death in 7 cases with the diagnoses: cyst of the kidney, renal sclerosis, renal failure, proteinuria, renal disease unspecified and malignant hypertension with renal involvement. It is concluded that renal involvement is characteristic of individuals with LMBB syndrome and seems to reduce life expectancy considerably.
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Comparison of the effectiveness of ultrasound-guided versus fluoroscopy-guided medial lumbar bundle branch block on pain related to lumbar facet joints: a multicenter randomized controlled non-inferiority study.
BMC Anesthesiol
March 2023
Department of Anesthesiology and Pain Medicine, Erasme Hospital, Université Libre de Bruxelles (ULB), Route de Lennik 808, 1070, Brussels, Belgium.
Article Synopsis
- A multicenter study compared ultrasound-guided lumbar medial branch block (LMBB) with fluoroscopy-guided LMBB for treating pain from lumbar facet joints.
- Fifty adults were randomly assigned to receive either method and assessed for pain relief and disability using various scales before treatment and at 1 week and 1 month post-procedure.
- Results showed that the ultrasound-guided method was just as effective as fluoroscopy in pain relief and had the added benefit of being irradiation-free, making it a viable alternative.
Retinitis pigmentosa in Laurence-Moon-Bardet-Biedl syndrome in India: Electronic medical records driven big data analytics: Report II.
Indian J Ophthalmol
July 2022
Srimati Kanuri Santhamma Center for Vitreo - Retinal Diseases, Hyderabad, Telangana, India.
Purpose: To describe the clinical presentation and demographic distribution of retinitis pigmentosa (RP) in Laurence-Moon-Bardet-Biedl (LMBB) syndrome patients.
Methods: This is a cross-sectional observational hospital-based study wherein 244 patients with RP in LMBB syndrome presenting to our hospital network between March 2012 and October 2020 were included. An electronic medical record database was used for data retrieval.
Transcriptome analysis reveals the activation of neuroendocrine-immune system in shrimp hemocytes at the early stage of WSSV infection.
BMC Genomics
March 2019
Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.
Background: Functional communications between nervous, endocrine and immune systems are well established in both vertebrates and invertebrates. Circulating hemocytes act as fundamental players in this crosstalk, whose functions are conserved during the evolution of the main groups of metazoans. However, the roles of the neuroendocrine-immune (NEI) system in shrimp hemocytes during pathogen infection remain largely unknown.
View Article and Find Full Text PDFSurvey of sonoanatomic distances for lumbar medial branch nerve blocks in healthy volunteers.
Korean J Pain
April 2014
Minimally Invasive Surgery Research Centre, Tehran University of Medical Sciences, Tehran, Iran.
Background: The precise knowledge of anatomy and the region of transverse process (TP) and superior articular processes (AP) and their distance from the skin are important in blocking and treating lumbar facet syndrome. Evaluation of these anatomic distances from 3rd and 5th lumbar vertebrae in both sides and in different body mass index (BMI) in healthy volunteers might improve knowledge of ultrasound (US) lumbar medial branch nerve blocks (LMBB).
Methods: Bilateral US in the 3rd and 5th lumbar vertebrae of 64 volunteers carried out and the distance between skin to TP and skin to AP was measured.
Laurence Moon Bardet Biedl syndrome associated with dyslipoproteinaemia.
J Indian Med Assoc
September 2011
Department of Pathology, BJ Medical College, Ahmedabad 380016.
Laurance Moon Bardet Biedl (LMBB) syndrome is a rare disorder characterised by retinitis pigmentosa, hexadactyly, obesity, mental retardation and hypogonadism. In the present case report the patient presented with the features of Laurence Moon Bardet Biedl syndrome in association with dyslipoproteinaemia.
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