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Introduction: cardioesophageal reflex may increase severity of chest pain and signs of myocardial ischemia on electrocardiogram (ECG), both in patients with and without significant coronary artery stenosis.

Objectives: the aim of the study was to evaluate the relationships between esophageal pH and pressure and clinical and electrocardiographic signs of myocardial ischemia.

Patients And Methods: in 129 consecutive patients with recurrent chest pain, 77 without significant coronary artery lesions in coronary angiography and 52 with myocardial ischemia, panendoscopy, pH-metry, manometry, and treadmill stress test were performed.

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Treatment results of 405 patients with Mallory-Weiss syndrome, X-ray gastric investigation in patients with severe bloating reflex were analyzed. Experimental part of the study involved rats and pigs, modeling esophageal and gastric rupture. Cardioesophageal and gastric cardial rupture happen in case of simultaneous sudden intragastric and intraabdominal hypertension, following the rule of Laplace.

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A 57-year-old man presented at our institution with central chest pain. Serial ECGs showed dynamic T-wave changes, suggesting the possibility of unstable angina. Urgent coronary angiography revealed an unexpected finding of a radio-opaque lesion seen in the xiphisternal region during screening.

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We report a novel technique for diagnosing a new cause of esophageal dysphagia in a patient without organic heart and esophageal disease. A coincidence between intermittent esophageal dysphagia and cardiac arrhythmia, frequent premature ventricular complexes (PVC) were confirmed by clinical observation, simultaneous ECG monitoring, and motility study. High-resolution esophageal manometry (HRM) revealed abnormal peristaltic waves only during frequent PVC.

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Evaluation of chest pain: a cardiology perspective for gastroenterologists.

Gastroenterol Clin North Am

March 2004

Sarver Heart Center, Room 5149, 1501 N. Campbell Ave., Tucson, AZ 85724, USA.

Evidence indicates that there is a strong cardioesophageal connection inpatients who experience esophageal or ischemic problems. Cardiologists and gastroenterologists often find the coexistence of symptoms and functional abnormalities, but determining causation is much more difficult. There isa need for better understanding of the phenomenon of cardiac and NCCP,among cardiologists and gastroenterologists.

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