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Histoplasmosis of the Head and Neck Region Mimicking Malignancy: A Clinic-Pathological Predicament.
Turk Patoloji Derg
May 2023
Department of Pathology, Tata Memorial Center, MUMBAI, INDIA.
Objective: Histoplasmosis is a systemic, deep mycotic infection caused by Histoplasma capsulatum. Disseminated histoplasmosis (DH) is synonymous with HIV seropositive immunocompromised individuals; however, isolated histoplasmosis involving the head and neck mucosal sites mimicking malignancy is a clinical predicament. The result, in a superficial biopsy with marked pseudoepitheliomatous hyperplasia (PEH), in a tertiary care cancer center where the number of squamous carcinomas far outnumber the infectious diseases, could be catastrophic.
View Article and Find Full Text PDFRelationship between microRNA genes incidence and cancer-associated genomic regions in canine tumors: a comprehensive bioinformatics study.
Funct Integr Genomics
March 2016
Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, P.O. Box: 76169133, Kerman, Iran.
The role of microRNAs (miRNAs) in human cancer biology has been confirmed on a genome-wide scale through the high incidence of these genes in cancer-associated regions. We analyzed the association between canine miRNA genes and cancer-associated regions (deleted and amplified regions) using previously published array of comparative genomic hybridization data on 268 canine cancer samples-comprising osteosarcoma, breast cancer, leukemia, and colorectal cancer. We also assessed this relationship apropos the incidence of miRNA genes in the CpG islands of the canine genome assembly.
View Article and Find Full Text PDF[Epidermoid carcinoma of the vulva during twin pregnancy: apropos of a case from the Lubumbashi university clinics].
Pan Afr Med J
September 2013
Service de Gynécologie-Obstétrique, Cliniques Universitaires de Lubumbashi, Unilu, BP 1825, Congo.
Carcinosarcoma ex non-recurrent pleomorphic adenoma composed of TTF-1 positive large cell neuroendocrine carcinoma and myofibrosarcoma: apropos a rare Case.
Head Neck Pathol
June 2013
Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
We present a carcinosarcoma ex non-recurrent pleomorphic adenoma composed of a large cell neuroendocrine carcinomatous component and a spindle cell sarcoma with myofibroblastic differentiation. The tumor contained a hyalinized transition zone where the classical PA appeared to acquire two different histopathological patterns of malignant transformation of the epithelial component. The carcinomatous component was strongly and diffusely positive for low-molecular weight cytokeratins (AE1-3), synaptophysin, thyroid transcription factor-1 and focally positive for chromogranin A.
View Article and Find Full Text PDF[Pheochromocytoma and pregnancy. Apropos of 1 case. Gynecol Obstet Fertil 2006; 34:323-5].
Gynecol Obstet Fertil
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