Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/088307389601100318 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Axon and muscle spindle hyperplasia in the myostatin null mouse.
J Anat
February 2011
School of Biological Sciences, Hopkins Building, University of Reading, Reading, UK.
Germline deletion of the myostatin gene results in hyperplasia and hypertrophy of the tension-generating (extrafusal) fibres in skeletal muscle. As this gene is expressed predominantly in myogenic tissues it offers an excellent model with which to investigate the quantitative relationship between muscle and axonal development. Here we show that skeletal muscle hyperplasia in myostatin null mouse is accompanied by an increase in nerve fibres in major nerves of both the fore- and hindlimbs.
View Article and Find Full Text PDFAfferent-inherent regulation of myosin heavy chain isoforms in rat muscle spindles.
Muscle Nerve
December 1997
Department of Anatomy, Northeastern Ohio Universities College of Medicine, Rootstown 44272-0095, USA.
Whether afferents exert their morphogenetic influence on spindles through release of trophic factors at intrafusal fiber junctions or via participation in proprioceptive pathways which modulate the motor activity to muscles was investigated by comparing myosin heavy chain (MHC) expression in intrafusal fibers after ablation of afferents (deafferentation, or DA) to the extensor digitorum longus (EDL) of adult rats or after ablation of the corresponding central processes of afferents to the spinal cord (central-process ablation, or CPA). DA and CPA elicited an exaggerated pedal plantarflexion, and hypertrophy of the EDL concomitant with atrophy of the soleus in the affected hindlimb. Frequencies and patterns of expression of seven MHCs expressed by intrafusal fibers in CPA muscles were indistinguishable from normal rats.
View Article and Find Full Text PDFHypertrophic intrafusal muscle fibers in infantile spinal muscular atrophy.
J Child Neurol
May 1996
Driscoll Children's Hospital, Corpus Christi, Texas, USA.
Ultra-high resolution scanning electron microscopic studies on the sarcoplasmic reticulum and mitochondria in various muscles: a review.
Scanning Microsc
March 1993
Department of Surgery, Kochi Medical School, Japan.
The three-dimensional structure of the sarcoplasmic reticulum (SR), transverse (T)-axial tubular system and mitochondria in various muscles was examined by means of ultra-high resolution scanning electron microscopy (SEM) after removal of the cytoplasmic matrices and myofilaments by the aldehyde-osmium-DMSO-osmium procedure. The striated muscles reviewed and presented are twitch and slow fibers of the frog, twitch and slow fibers of the chicken, twitch extrafusal fibers and intrafusal fibers of the rat, and cardiac muscle fibers of the rat and dog. In all of these striated muscle fibers, T-tubules run transversely and are coupled with terminal cisternae forming triads or dyads.
View Article and Find Full Text PDFHypertrophic cardiomyopathy with mitochondrial myopathy. A new phenotype of complex II defect.
Jpn Heart J
January 1993
Neuromuscular Center, University of Padova, Italy.
Two brothers, 25 and 19 years old, were affected by asymmetrical hypertrophic cardiomyopathy. The older brother had waddling gait and weakness of the proximal girdle muscles, while the younger had a broad-based gait and weakness of selected limb girdle muscles. EMG exam was myopathic.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!