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Comparison of outcomes between anticoagulation and antiplatelet therapies for intracranial arterial dissections.
Front Neurol
December 2024
Department of Neurology, Ajou University School of Medicine, Suwon, Republic of Korea.
Background: This study aimed to evaluate real-world data on the differences in outcomes between antiplatelet (AP) and anticoagulation (AC) therapies for intracranial arterial dissection (IAD).
Methods: This study included patients with symptomatic unruptured IAD between 2010 and 2021 that were treated with anti-thrombotics. Patients were dichotomized to AC and AP based on a treatment policy analysis.
Treatment of Terminal Syrinx With a Syringo-Subarachnoid Shunt and the Novel Use of a Titanium Knot Fastener: A Case Report.
Cureus
November 2024
Neurological Surgery, University of Rochester Medical Center, Rochester, USA.
A syrinx involves cystic dilation of the central canal of the spinal cord due to the accumulation of cerebrospinal fluid and often results in a neurological deficit. While treatment options vary, surgical management is often utilized and requires an open durotomy. A 70-year-old female presented with one year of progressive low back pain with associated leg numbness, urinary incontinence, bilateral foot drop, and imbalance resulting in multiple falls.
View Article and Find Full Text PDFRisk factor analysis and nomogram model establishment for in-hospital death of elderly patients with surgically treated traumatic acute subdural hematoma.
Medicine (Baltimore)
December 2024
Department of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou City, China.
The purpose of this study was to investigate the risk factors for in-hospital death in elderly patients with surgically treated traumatic acute subdural hematoma (ASDH) and to construct a nomogram model for in-hospital death risk prediction. We analyzed 104 elderly patients who underwent decompressive craniotomy (DC) for isolated traumatic ASDH between May 2013 and May 2021 in our department. Independent factors for in-hospital death were identified via univariate and multivariate logistic regression analyses, and a nomogram model was constructed and validated.
View Article and Find Full Text PDFSpinal cord-spinal canal disproportion following treatment for syringomyelia associated with Chiari malformation type I: illustrative case.
J Neurosurg Case Lessons
December 2024
Department of Neurological Surgery, Virginia Commonwealth University, Richmond, Virginia.
Article Synopsis
- * After successful surgery to relieve pressure, the patient underwent treatment for SAH and showed significant improvement, with his symptoms resolving and no further complications over four years.
- * The report is significant as it presents the first known case of this type of hemorrhage following the surgery and suggests a potential relationship between syringomyelia and the diameter of the spinal canal.
Cerebral Aneurysm: Filling the Gap Between Pathophysiology and Nanocarriers.
Int J Mol Sci
November 2024
"Nicolae Oblu" Clinical Hospital, 700309 Iasi, Romania.
Intracranial aneurysms, characterized by abnormal dilations of cerebral arteries, pose significant health risks due to their potential to rupture, leading to subarachnoid hemorrhage with high mortality and morbidity rates. This paper aim is to explore the innovative application of nanoparticles in treating intracranial aneurysms, offering a promising avenue for enhancing current therapeutic strategies. We took into consideration the pathophysiology of cerebral aneurysms, focusing on the role of hemodynamic stress, endothelial dysfunction, and inflammation in their development and progression.
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