Hematopoietic growth factors in clinical practice.

Objective: To review the hematopoietic growth factors (HGFs) as they relate to hematopoiesis, dosing, administration, toxicities and clinical indications.

Data Sources: Research studies, abstracts, review articles, product package inserts, and book chapters pertaining to HGFs.

Conclusions: HGFs are essential components for the development of blood cells. Recombinant DNA technology and the availability of HGFs have significantly altered the care of patients with cancer and bone marrow disorders.

Implications For Nursing Practice: Nurses can play a major role in assisting patients, families, and various consumers by providing education about HGFs as well as their indications, schedule, methods of administration, and toxicities. Familiarity with the HGFs and the literature available can assist nurses in developing management strategies for patients receiving these agents.