Silicone elastomer particles (Silastic silicone elastomer, Dow Corning, Midland, MI), polymethylmethacrylate particles, and monosodium urate particles smaller than 10 microns were injected into a rat subcutaneous air pouch lined with synovial membrane-like cells. Inflammatory exudate from the air pouch was retrieved at 6 hours, 24 hours, 48 hours, and 72 hours after injection. White blood cell count, tumor necrosis factor, and prostaglandin E2 were measured in the exudate. White blood cell and tumor necrosis factor levels in the exudate were the highest for the silicone group at 6 and 24 hours. Prostaglandin E2 was also significantly higher in the silicone group at 24 hours. We conclude that the acute inflammation is particle-type specific and that Silicone elastomer particles are acutely inflammatory.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0363-5023(96)80369-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative Evaluation of the Dimensional Accuracy of Silicone-Based Putty Reline Impressions with Different Spacer Acquisition Techniques in Fixed Partial Dentures.
Med Sci Monit
January 2025
Department of Prosthetic Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
BACKGROUND A tooth preparation's clinical requirements and geometric configurations should take precedence over material characteristics when advocating for putty reline impression techniques for permanent restorations, since they require a technically sensitive spacer for light body elastomer. We evaluated the linear dimensional accuracy of vinyl polysiloxane-based putty reline impressions with different spacer acquisition techniques in short-span and long-span fixed partial dentures (FPD). MATERIAL AND METHODS A typodont tooth set simulated a 3-unit (short-span) and a 5-unit (long-span) FPD.
View Article and Find Full Text PDFEvaluating Cost-effectiveness and Mixing Efficacy for Elastomeric and Temporary Restorative Material Using Two Mixing Tips: A SEM-EDS Analysis.
J Contemp Dent Pract
September 2024
Department of Prosthodontics and Crown & Bridge, Bharati Vidyapeeth Deemed to be University, Dental College and Hospital, Pune, Maharashtra, India, ORCID: https://orcid.org/0009-0008-7338-1699.
Aim: This study aimed to compare the mixing efficacy and cost-effectiveness of new T-mixer tips against the standard double helical tips for a light-body elastomeric impression and a temporary/interim restorative material using a scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopy.
Methodology: Automixed samples ( = 16) were divided into four groups of four samples each: Samples that were mixed with Helical tip for elastomer, T-mixer tip for elastomer, Helical tip for interim restorative material, and T-mixer tip for interim restorative material. These samples were then evaluated for SEM analysis.
Development and characterization of silicone-based tissue phantoms for pulse oximeter performance testing.
J Biomed Opt
June 2024
Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, Maryland, United States.
Significance: Pulse oximeter measurements are commonly relied upon for managing patient care and thus often require human testing before they can be legally marketed. Recent clinical studies have also identified disparities in their measurement of blood oxygen saturation by race or skin pigmentation.
Aim: The development of a reliable bench-top performance test method based on tissue-simulating phantoms has the potential to facilitate pre-market assessment and the development of more accurate and equitable devices.
Bioinspired surface structures for added shear stabilization in suction discs.
Sci Rep
January 2025
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, 02134, USA.
Many aquatic organisms utilize suction-based organs to adhere to diverse substrates in unpredictable environments. For multiple fish species, these adhesive discs include a softer disc margin consisting of surface structures called papillae, which stabilize and seal on variable substrates. The size, arrangement, and density of these papillae are quite diverse among different species, generating complex disc patterns produced by these structures.
View Article and Find Full Text PDFThermal Actuators Relying on Elastomer-Dispersed Liquid Crystals: From Imines with Supramolecular Chirality and Ferroelectricity to Soft Robots.
ACS Appl Mater Interfaces
January 2025
Department of Inorganic Polymers, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Gr. Ghica Voda 41A, 700487 Iasi, Romania.
The locomotion of various organisms relies on the alternated elongation-contraction of their muscles or bodies. Such biomimicry can offer a promising approach to developing soft robotic devices with improved mobility and efficiency. Most strategies to mimic such motions rely on reversible size modifications of some materials upon exposure to external stimuli.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!