AI Article Synopsis
- Researchers studied the use of immunostimulants dibasole and methyluracil to boost neutralizing antibodies against poliovirus types I, II, and III following vaccination with live polio vaccine in rabbits.
- The findings indicated that these drugs, particularly methyluracil, enhance the immune response.
- A repeated immunization was necessary to effectively produce antibodies for poliovirus type III.
Article Abstract
A possibility to use immunostimulator dibasole and methyluracil to increase [correction of decrease] the level of neutralising antibodies to polioviruses [correction of polyviruses] of types I, II, III in response to immunization by the alive poliomyelitis vaccine was studied in experiments on rabbits. The higher level of immune response when using the mentioned drugs, especially methyluracil, has been established; repeated immunization is needed to develop antibodies to poliovirus [correction of polyavirus] of type III.
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