Conservative medical treatment of acute occlusion of the extracranial internal carotid artery usually gives mediocre results. When a major neurological deficit is involved, mortality can reach 16 to 55%, morbidity due to definitive deficit 40 to 69% and cure only 2 to 12%. It is thus logical to attempt revascularization as an emergency procedure. In situ intraarterial fibrinolysis is appropriate for acute occlusion in the intracranial territory of the internal carotid involving severe neurological deficits but surgery is more adapted and safer for acute occlusion of the extra-cranial internal carotid. In a personal series of 8 patients, we had 1 death, 1 aggravation, 1 improvement and 5 "cures" (62.5%). Based on data in the literature and our experience, we assessed the advantages of emergency surgery (immediate and definitive re-establishment of the carotid flow and vascularization of the hemisphere before installation of irreversible brain damage) and conditions suggesting chances of success: 1) diagnosis by noninvasive echo-Doppler of the cervical vessels and transcranial Dopler, without preoperative arteriography or CT-scan. 2) operation before 6 hours, 3) quality of the desobstruction, 4) no post-operative anti-coagulant treatment, 5) control of post-operative episodes of hypertension.
Download full-text PDF |
Source |
---|
NMC Case Rep J
December 2024
Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Shunt dependence syndrome is a serious long-term complication characterized by symptoms and signs of increased intracranial pressure with normal-sized lateral ventricles after several years of arachnoid cyst-peritoneal shunting. It is easy to misdiagnose and overlook when combined with sinus stenosis, thus delaying treatment. Here, we present a 35-year-old man with an unexplained headache and binocular horizontal diplopia with high intracranial pressure.
View Article and Find Full Text PDFEmerg Med Int
January 2025
Nanjing Comprehensive Stroke Center, Affiliated Nanjing Brain Hospital of Nanjing Medical University, Nanjing, China.
Ischemic stroke is one of the major emergency diseases leading to death and disability worldwide, characterized by its acute onset and the urgent need for prompt medical intervention to reduce mortality and long-term disability. Chronic terminal internal carotid artery and/or middle cerebral artery occlusion (CTI/MCAO) is an important subtype of intracranial artery occlusive disease. The superficial temporal artery-to-MCA (STA-MCA) bypass has been proposed to improve cerebral blood flow (CBF) and cerebrovascular reserve (CVR), potentially enhancing neurological outcomes.
View Article and Find Full Text PDFBiomed Eng Online
January 2025
Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810008, China.
Recently, the incidence rate and mortality of various acute or chronic vascular occlusive diseases have increased yearly. As one of the most effective measures to treat them, vascular stents have been widely studied by researchers, and presently, the most commonly used is a drug-eluting stent, which reduces the process of rapid endothelialization because the drug is not selective. Fortunately, with the discovery and exploration of micro-nanostructures that can regulate cells selectively, reducing the incidence of "intravascular restenosis" and achieving rapid endothelialization simultaneously are possible through a special structure that cannot only improve endothelial cells (ECs), but also inhibit smooth muscle cells (SMCs).
View Article and Find Full Text PDFSci Rep
January 2025
Department of Neurology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Acute internal carotid artery occlusion (AICAO) can result in malignant cerebral edema and unfavorable patient outcomes. This study evaluated the utility of transcranial Doppler (TCD) in assessing contralateral flow compensation and predicting outcomes in patients with AICAO. We enrolled 51 patients within 6 h of symptom onset and conducted TCD examinations to evaluate collateral circulation.
View Article and Find Full Text PDFEur Heart J Digit Health
January 2025
Lewisham and Greenwich NHS Trust, UK.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!