Phosphatidylserine-mediated adhesion of T-cells to endothelial cells.

Biochem J

Department of Cellular Physiology, Babraham Institute, Cambridge, UK.

Published: July 1996

Phosphatidylserine was exposed on the surface of human umbilical endothelial cells (ECV304) a few minutes after adding thrombin in vitro, as monitored by prothrombinase assays with and without annexin V. Jurkat T cells adhered to the thrombin-treated cells. The adhesion was inhibited by annexin V, indicating that it was mediated by exposed phosphatidylserine on the endothelial cells.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1217493PMC
http://dx.doi.org/10.1042/bj3170343DOI Listing

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