After the enthusiasm given by the new treatment techniques of complicated portal hypertension (sclerotherapy, TIPS and liver transplantation), various authors in the literature are considering the role of derivative surgery in the treatment of this affection, due to their consolidated experiences and with a long term follow-up. The authors analyse their own long experience, regarding 104 side-to-side porto-caval shunt. It has been done a complete follow-up, of 71 patients, for a period lasting from 4 to 20 years from the operation. Intraoperative mortality was 5,7%, global morbidity was 28%. Haemorrhagic recurrence from rupture of oesophageal varices was found in 2 cases (1 soon after and the other 3 months from the operation). 5 years survival was depending from Child score (96% Child A, 66,4 Child B, 25% Child C) and from the ethology of cirrhosis (70% for alcoholic cirrhosis and 80% for post-hepatitis cirrhosis). The survival was anyhow mainly connected with the persistence of alcohol abuse. The EPS appeared or became worse after the operation in 12 patients out of 71 checked (16.7%). It has never made a patient enable to lead an ordinary life. Due to the results of their own experience, the authors underline the efficacy of side-to-side porto-caval shunt in the prevention of the haemorrhagic recurrence from oesophageal rupture. In selected patients, Child A and B, not responding to the endoscopic treatment and in elective operations, the mortality was very well contained with a good prevention even after many years and a very small occurrence of EPS. For all those reasons, the side-to-side porto-caval shunt still keeps its validity also towards the selective shunts that are much more difficult technically and that can't be done on ascitic patients.
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Transplant Proc
September 2012
Hepatobiliary Surgery-Liver Transplant Unit, A. Cardarelli Hospital, Naples, Italy.
Objective: Our objective was to perform a retrospective study that described the anastomosis technique as well as the complications of side-to-side cavo-caval reconstruction.
Patients And Methods: From June 1998 to April 2011, we performed 284 liver transplantations including 10 adults with live donor organs. In all cases but 2 (272), cavo-caval reconstruction was performed using side-to-side cavo-caval (STSCC) anastomosis.
J Transplant
July 2011
Department of Surgery and Transplantation, San Martino Hospital, University of Genoa, Monoblocco IV, Largo R. Benzi 10, 16132 Genoa, Italy.
Two-stage liver transplantation (LT) has been reported for cases of fulminant liver failure that can lead to toxic hepatic syndrome, or massive hemorrhages resulting in uncontrollable bleeding. Technically, the first stage of the procedure consists of a total hepatectomy with preservation of the recipient's inferior vena cava (IVC), followed by the creation of a temporary end-to-side porto-caval shunt (TPCS). The second stage consists of removing the TPCS and implanting a liver graft when one becomes available.
View Article and Find Full Text PDFHPB Surg
July 2011
Department of Surgery, Liver Transplantation Unit, Niguarda "Cà Granda" Hospital, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.
We describe a modified technique of side-to-side cavo-cavostomy by Dacron interposition prosthesis during a super urgent liver transplantation. A liver graft from a deceased donor was immediately requested on a top priority basis as a consequence of massive bleeding during extended left hepatectomy for a huge hepatic haemangioma arising from the caudate lobe. Veno-venous bypass was employed during anhepatic phase but it was disconnected due to severe fibrinolysis and hypothermia.
View Article and Find Full Text PDFTransplant Proc
May 2010
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento assistenziale di Chirurgia Generale e Trapianti d'Organo, Università degli Studi di Padova, Padova, Italy.
Tumor progression before orthotopic liver transplantation (OLT) is the main cause of dropouts from waiting lists among patients with hepatocellular carcinoma (HCC). Performing a porto-caval shunt (PCS) before parenchymal liver transection has the potential to allow an extended hepatectomy in patients with decompensated liver cirrhosis, reducing portal hyperflow and therefore the sinusoidal shear-stress on the remnant liver. We report the case of a 59-year-old man affected by hepatitis C virus (HCV)-related decompensated liver cirrhosis (Child Pugh score presentation, C-10; Model for End Stage Liver Disease score, 18) and HCC (2 lesions of 2 and 2.
View Article and Find Full Text PDFTranspl Int
June 2003
Division of Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, 980-0574 Sendai, Miyagi, Japan,
In partial-liver transplantation, the use of small grafts sometimes results in graft failure, usually caused by portal hypertension after transplantation (Tx). Portal hypertension after Tx can be decreased with a porto-caval shunt (PCS). The purpose of this study is to clarify the effect of the PCS on extremely reduced-size liver Tx.
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