The first experience with the immunotherapy of staphylococcal sepsis with heterologous anti-staphylococcal gamma-globulin (cozym) with a high antitoxin titer--above 200 A. E./ml--is generalized in the article. The results of the anti-staphylococcal gamma-globulin use in 19 patients are analysed. A comparative evaluation of the drug related to the donor preparation is set forth. The advantages of heterologous anti-staphylococcal gamma-globulin are grounded.
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J Basic Microbiol
November 1990
Department of Microbiology and Immunology, Technical University AGH, Krakow, Poland.
The interactions between polymorphonuclear cells (PMN), Staphylococcus saprophyticus cells and rabbit antibodies against Staphylococcus aureus V8 serine proteinase or normal rabbit serum proteins were investigated. The effect of opsonization on phagocytosis due to human peripheral polymorphonuclear cells was measured. The results were as follows: phagocytosis index values were relatively increased after the incubation of PMN cells with anti-serine proteinase gamma-globulin serum fraction, anti-serine proteinase IgG, non-immunized rabbit serum or with complement.
View Article and Find Full Text PDFVestn Khir Im I I Grek
April 1979
The first experience with the immunotherapy of staphylococcal sepsis with heterologous anti-staphylococcal gamma-globulin (cozym) with a high antitoxin titer--above 200 A. E./ml--is generalized in the article.
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