Cell death by apoptosis occurs in a number of normal tissue systems including the nervous system. It is a highly specific process, which requires new gene expressions and the production of new proteins. The genetic information determines biochemical and morphological sequence of events in the cell undergoing apoptosis. This review focuses on the recent informations concerning the participation of the genes in the survival and death of neurons in the central nervous system and the effect of the anti-cancer drugs on the induction of apoptosis in the cell.
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