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Biomechanical analysis of a newly designed and 3D printed plate-locking interbody cage: an observational study of finite element analysis.
Sci Rep
January 2025
Department of Orthopaedic Trauma, The Second Affiliated Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian, 116027, Liaoning, China.
Anterior cervical interbody fusion (ACDF) has become a classic surgical procedure for the treatment of cervical degenerative diseases, and various interbody cages are widely used in this procedure. We used 3D printing technology to produce a new type of plate-locking cage, anticipating to achieve high fusion rate with the high biomechanical stability. This study is to compare the biomechanical characteristics between a newly designed interbody cage and a conventional Zero-profile cage during ACDF using finite element analysis.
View Article and Find Full Text PDFRaptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity.
Cell Res
January 2025
Department of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, China.
Sleep deficiency is associated with obesity, but the mechanisms underlying this connection remain unclear. Here, we identify a sleep-inducible hypothalamic protein hormone in humans and mice that suppresses obesity. This hormone is cleaved from reticulocalbin-2 (RCN2), and we name it Raptin.
View Article and Find Full Text PDFEvolution of Sagittal Spinal Alignment During Pubertal Growth: A Large-Scale Study in a Chinese Pediatric Population.
J Bone Joint Surg Am
January 2025
Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People's Republic of China.
Background: Previous studies have reported normative data for sagittal spinal alignment in asymptomatic adults. The sagittal spinal alignment change in European children was recently reported. However, there is a lack of studies on the normative reference values of sagittal spinal and pelvic alignment and how these parameters change at different growth stages in Chinese children.
View Article and Find Full Text PDFThe association between dietary inflammatory index and bone health in US adolescents: Analysis of the NHANES data.
Bone Rep
March 2025
Department of pediatrics, Liaocheng Second People's Hospital, Liaocheng 252600, China.
Introduction: Adolescents with a lower peak bone mineral density (BMD) and bone mineral content (BMC) have an elevated risk of osteoporosis in adulthood. The impact of diet on bone health, particularly its role in managing inflammation, which is a key factor in bone health, is gaining wider recognition. Despite evidence that anti-inflammatory diets can enhance bone health, the link between the dietary inflammatory index (DII) and bone health among US adolescents has not been thoroughly investigated.
View Article and Find Full Text PDFRescue of Interfragmentary Compression in Screw Stripping Failures: The Efficacy of NiTiNOL.
J Foot Ankle Surg
January 2025
Enovis Foot & Ankle, Atlanta, GA; Georgia Institute of Technology, Atlanta, GA. Electronic address:
Orthopedic screws are widely used to achieve bone reduction, compression, and construct stability. However, the relationship between insertion torque, interfragmentary compression, and fixation strength, especially when comparing standard screws with NiTiNOL/sustained dynamic compression (SDC), has not been thoroughly investigated. This study measured insertion torque, interfragmentary compression, and fixation strength for two types of headed orthopedic devices-standard and SDC-using solid foam bone replicates and cadaver validation.
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