[Effect of perinatal risk factors on treatment outcome in newborns with hypoxic-ischemic encephalopathy].

In 99 newborns with hypoxic-ischemic encephalopathy (22 with mild, 53 with moderate and 24 with severe stage) correlation between birth weight, low Apgar score, high-risk pregnancy and delivery and stage of encephalopathy and results of the treatment was made. Low Apgar score (< 3) had significantly influence on the development of severe encephalopathy. Most important perinatal risk factor was abnormal delivery. Especially high mortality because of moderate and severe stage of encephalopathy in prematures with intracranial hemorrhage and congenital infection was noted. Full-term babies died because of others causes. It was shown, that unfavourable outcome of neonatal encephalopathy depends mainly on high-risk delivery.