A clinical trial, based on the guidelines of the American Dental Association, was conducted to evaluate the efficacy and safety of Bio-Bright, a new manually rotating toothbrush. The brush was used by 28 adults and compared to a group of 26 adults who used an ADA-accepted toothbrush (Oral-B 35). Examinations were recorded for safety, plaque level, gingival inflammation and gingival bleeding at baseline, 15 days and one month. Analysis of the data revealed no statistically significant differences between the two groups at any of the measurement periods. When calculating the cumulative longitudinal effect on plaque increase or decrease, a consistent and statically significant advantage was revealed for the Bio-Bright group, as compared to the control. No significant differences were demonstrated when comparing safety, gingival, and bleeding indices between the two groups.
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