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Cytokine therapy of acute radiation syndrome.
Best Pract Res Clin Haematol
December 2024
Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, SW7 2AZ, UK.
Radiological accidents/incidents are common with nearly 400 reported since 1944 exposing about 3000 people to substantial doses of ionizing radiations with 127 deaths. Damage to hematopoietic stem and progenitor cells with resulting bone marrow failure is a common consequence of exposure to whole body acute high-dose and -dose-rate ionizing radiations and is termed hematopoietic-acute radiation syndrome, or H-ARS. Therapy of H-ARS includes transfusions, anti-bacterial and -viral drugs, molecularly-cloned hematopoietic growth factors and hematopoietic cell transplants.
View Article and Find Full Text PDFExtracorporeal Membrane Oxygenation in the Treatment of Acute Elemental Mercury Inhalation Toxicity.
Chest
March 2025
Northwell Health Division of Medical Toxicology, North Shore University Hospital, Manhasset, NY.
Inhalation of elemental mercury is a rare cause of ARDS, with limited published case reports to provide guidance regarding disease progression and management. Although extracorporeal membrane oxygenation (ECMO) has been used to treat toxin-induced lung injury, its application to initial treatment and long-term recovery for inhalation of mercury remains undescribed. We present a case of a 56-year-old man who works at a thermometer factory presenting with severe ARDS secondary to inhaled elemental mercury with confirmatory blood and urine mercury levels.
View Article and Find Full Text PDFFactors associated with prehospital and in-hospital delays in acute ischaemic stroke care in Indonesia: a systematic review.
BMJ Open
March 2025
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Objectives: This systematic review examines prehospital and in-hospital delays in acute stroke care in Indonesia.
Design: Systematic review adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Data Sources: We conducted a thorough search across 11 databases, ClinicalTrials.
Rurality Status and Cardiovascular Events/Survival in Older Men With Prostate Cancer.
J Natl Compr Canc Netw
March 2025
5Department of Medicine, Medical College of Georgia at Augusta University, Augusta, GA.
Background: Rural areas have higher cardiovascular disease (CVD) incidence and age-adjusted mortality rates in the general population. However, the impact of rurality on CVD development and outcomes in patients with prostate cancer (PC) remains unclear.
Patients And Methods: This retrospective cohort study used the SEER-Medicare database to analyze males aged ≥65 years diagnosed with PC between 2009 and 2017.
Bovine Coronavirus in diarrheic pre-weaned calves in Egypt: prevalence, risk factors, and the associated biochemical alterations.
Trop Anim Health Prod
March 2025
Department of Animal Medicine, Division of Internal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.
Bovine coronavirus (BCoV) is a common viral enteric pathogen responsible for diarrhea in newborn calves. Despite its economic significance, there is limited research on this virus in Egypt. This study aimed to detect the prevalence of BCoV, the associated risk factors, and the biochemical changes during infection.
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