What is meant by 'rheumatoid'?

Ann Rheum Dis

Published: June 1996

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1010194PMC
http://dx.doi.org/10.1136/ard.55.6.403-aDOI Listing

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Background: The ability to predict rheumatoid arthritis (RA) flares between clinic visits based on real-time, longitudinal patient-generated data could potentially allow for timely interventions to avoid disease worsening.

Objective: This exploratory study aims to investigate the feasibility of using machine learning methods to classify self-reported RA flares based on a small data set of daily symptom data collected on a smartphone app.

Methods: Daily symptoms and weekly flares reported on the Remote Monitoring of Rheumatoid Arthritis (REMORA) smartphone app from 20 patients with RA over 3 months were used.

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Conventional synthetic (cs) and targeted synthetic (ts) disease-modifying antirheumatic drugs (DMARD) have potential interactions with a multitude of drugs. Furthermore, they sometimes have a lower therapeutic index, particularly in cases of limited organ functions. The aim of this work was to establish evidence-based recommendations on the therapeutic use of DMARDs in the context of drug interactions and dosage recommendations.

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Article Synopsis
  • Rheumatoid arthritis (RA) is a chronic inflammatory condition causing joint pain, with biologics being effective treatments now approved for those with moderately active disease, thanks to recent guideline changes (NICE TA715).
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There is an increasing recognition of the importance of patient engagement and involvement in health research, specifically within the field of rheumatology. In general, researchers in this specialty appreciate the value of patients as partners in research. In practice, however, the majority of researchers does not involve patients on their research teams.

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