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The arterial oxygen status of clinically healthy dogs at an altitude of 1250 metres. | LitMetric

The arterial oxygen status of clinically healthy dogs at an altitude of 1250 metres.

J S Afr Vet Assoc

Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.

Published: December 1995

AI Article Synopsis

  • A study was conducted on 6 healthy blood donor dogs at an altitude of 1250 meters to assess their blood-gas, acid-base, and arterial oxygen status.
  • The researchers measured several derived variables related to oxygen status, using a computer program originally designed for humans, and found that there were no significant differences in the measurements taken on two occasions three days apart.
  • The average values obtained for oxygen extraction tension (Px), extractable oxygen concentration (Cx), and oxygen compensation factor (Qx) in the dogs were comparable to those reported for humans.

Article Abstract

The blood-gas, acid-base, and arterial oxygen status of 6 healthy blood donor dogs was studied at an altitude of 1250 metres on 2 occasions 3 days apart. The values, and repeatability, of a number of derived variables that describe oxygen status, including oxygen extraction tension (Px), extractable oxygen concentration (Cx), and oxygen compensation factor (Qx) were established in clinically healthy dogs. The Oxygen Status Algorithm computer programme which was developed for use in humans was used to calculate these derived variables. 2,3-Bisphosphoglycerate concentrations were measured spectrophotometrically and compared with 2,3-bisphosphoglycerate concentrations calculated by the Oxygen Status Algorithm. This study revealed that there were no significant differences between the means of any of the variables used to describe oxygen status on the two occasions. The mean Px of 38.74 mmHg, Cx of 4.38 ml/dl, and Qx of 1.2 were similar to those reported for man.

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