A total of 135 subjects, 54 of them HIV infected and 81 donors (controls) were examined by microscopy and laser flow cytometry. A certain reduction of the total leukocyte count and of absolute lymphocyte count in the peripheral blood and a comparatively higher percent content of these cells were observed in HIV infected subjects examined for the first time. Laser flow cytometry proved to be a more informative method both for the assessment of the total count of leukocytes (p < 0.05) and for a complex assessment of cell counts (total leukocyte count, absolute and relative counts of lymphocytes) in the peripheral blood (p < 0.01) of patients with HIV infection.

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