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Detection of Insertion/Deletions (InDel) Within Five Clock Genes and Their Associations with Growth Traits in Four Chinese Sheep Breeds.
Vet Sci
January 2025
College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Organisms have the capacity to detect day-night fluctuations through oscillators regulated by circadian clock genes, which are crucial for regulating various biological processes. Numerous studies have demonstrated a marked association between these genes and various growth traits of sheep. This study identified polymorphisms at 23 potential loci within five clock genes in four Chinese sheep breeds.
View Article and Find Full Text PDFIdentification and characterization of ClAPRR2, a key candidate gene controlling watermelon stripe color.
Plant Sci
January 2025
Key Laboratory of Biology and Genetic Improvement of Horticulture Crops (Northeast Region), Ministry of Agriculture and Rural Affairs, College of Horticulture and Landscape Architecture, Northeast Agricultural University, Harbin 150030, China; College of Horticulture and Landscape Architecture, Northeast Agricultural University, Harbin 150030, China. Electronic address:
The stripe color of watermelon is a vital commercial trait and is the focus of attention of consumers and researchers. However, the genetic determinants of watermelon stripe color are incompletely understood. Based on the results of preliminary localization studies, we constructed a large-capacity F generation population (710 plants) using light-green striped ZXG1555 and green-striped Cream of Saskatchewan (COS) watermelon strains as parental lines for fine mapping.
View Article and Find Full Text PDFSCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function.
EMBO Rep
November 2024
CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110024, India.
In this study, we characterize a novel lncRNA-producing gene locus that we name Syntenic Cardiovascular Conserved Region-Associated lncRNA-6 (scar-6) and functionally validate its role in coagulation and cardiovascular function. A 12-bp deletion of the scar-6 locus in zebrafish (scar-6) results in cranial hemorrhage and vascular permeability. Overexpression, knockdown and rescue with the scar-6 lncRNA modulates hemostasis in zebrafish.
View Article and Find Full Text PDFNovel allelic variations in and contribute to tannin absence in sorghum.
Mol Breed
March 2024
National Key Laboratory of Wheat Improvement, College of Life Sciences, Shandong Agricultural University, Tai'an, 271018 China.
Unlabelled: Sorghum is an important food crop commonly used for brewing, feed, and bioenergy. Certain genotypes of sorghum contain high concentrations of condensed tannins in seeds, which are beneficial, such as protecting grains from herbivore bird pests, but also impair grain quality and digestibility. Previously, we identified and , each with three recessive causal alleles, regulate tannin absence in sorghum.
View Article and Find Full Text PDFMitochondrial DNA editing in potato through mitoTALEN and mitoTALECD: molecular characterization and stability of editing events.
Plant Methods
January 2024
CREA, Research Centre for Vegetable and Ornamental Crops, via Cavalleggeri 25, 84098, Pontecagnano, SA, Italy.
Article Synopsis
- The study focused on evaluating two TALE-based methods for editing the mitochondrial genome of potato: mitoTALEN (using FokI nuclease) and mitoTALECD (using DddA cytidine deaminase).
- Both methods targeted the same mitochondrial sequence (orf125), resulting in a variety of mutations -- mitoTALEN induced deletions of varying sizes through homologous recombination, while mitoTALECD produced single nucleotide mutations.
- The findings showed that both editing techniques successfully modified the mitochondrial genome with high efficiency, enabling comparisons of their effectiveness, precision, and stability in subsequent plant generations.
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