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The Role of Gut Microbiota in Shaping Immune Responses in Tephritidae Fruit Fly and Prospective Implications for Management.

Neotrop Entomol

January 2025

State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Bio Pesticide and Chemical Biology, MOE, College of Plant Protection, Fujian Agriculture and Forestry Univ, Fuzhou, China.

The interaction of microbial communities with host immunity has become one of the most explored research areas with significant implications for pest control strategies. It has been found that the gut microbiota plays substantial roles in immune response regulation and host-gut microbiome symbiosis, as well as in pathogen resistance and overall fitness in Tephritidae fruit flies that are major pests of agricultural importance. In this review, we discuss the modulation of immune responses of Tephritidae fruit flies by the gut microbiota with particular emphasis on the general interactions between microbiota and the immune system.

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Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides.

Nat Commun

January 2025

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.

Commensal bacteria affect host health by producing various metabolites from dietary carbohydrates via bacterial glycometabolism; however, the underlying mechanism of action remains unclear. Here, we identified Streptococcus salivarius as a unique anti-obesity commensal bacterium. We found that S.

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A Comprehensive OBD Data Analysis Framework: Identification and Factor Analysis of High-Emission Heavy-Duty Vehicles.

Environ Pollut

January 2025

Tianjin Key Laboratory of Urban Transport Emission Research & State Environmental Protection Key Laboratory of Urban Ambient Air Particulate Matter Pollution Prevention and Control, College of Environmental Science and Engineering, Nankai University, Tianjin, 300071, China.

On-Board Diagnostic (OBD) systems enable real-time monitoring of NOx emissions from heavy-duty diesel vehicles (HDDVs). However, few studies have focused on the root cause analysis of these emissions using OBD data. To address this gap, this study proposes an integrated analysis framework for HDDV NOx emissions that combines data processing, high-emission vehicle identification, and emission cause analysis.

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Evaluation of interspecies correlation estimation models to increase taxonomic diversity while reducing reliance on animal testing for chemicals evaluated under the Toxic Substances Control Act.

Integr Environ Assess Manag

January 2025

Office of Chemical Safety Office Pollution Prevention, Office of Pollution Prevention and Toxics, US Environmental Protection Agency, Washington, DC, United States.

The U.S. Environmental Protection Agency is committed to the implementation of new approach methodologies (NAMs) to enhance the scientific basis for chemical hazard assessments.

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Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or , but the keys to some important biomedical questions may simply not be found in these.

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