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Psychometric Properties of the Critical Appraisal Tool for Anatomical Meta-Analysis.
Clin Anat
January 2025
Division of Anatomy, Department of Radiology, Weill Cornell Medicine, New York, New York, USA.
The hallmark of evidence-based anatomy (EBA) is the anatomical meta-analysis (AMA). The Critical Appraisal Tool for Anatomical Meta-Analysis (CATAM) was recently published to enable users to appraise AMAs quickly and effectively. The tool is valuable for students and clinicians who need to judge the quality of AMAs, which informs clinical decision making and results in better patient care.
View Article and Find Full Text PDFProtocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer.
Radiother Oncol
January 2025
Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address:
Purpose: To report on quality assurance (QA) and protocol adherence (PA) in a multicentre phase III trial for head and neck cancer, evaluate patterns of protocol deviations and investigate the effect of PA on study outcomes.
Methods: All 221 patients from the ARTFORCE trial (NCT01504815) were included in this study. Pre- and per-treatment QA measures included protocol guidelines, a dummy run, early case reviews and trial meetings.
Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network analyses.
Eur Neuropsychopharmacol
January 2025
Charité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA; The Zucker Hillside Hospital, Northwell Health, New York, USA; Feinstein Institutes for Medical Research, Center for Psychiatric Neuroscience, Manhasset, New York, USA. Electronic address:
Article Synopsis
- The COH-FIT study is a large, multi-country survey aimed at identifying factors affecting wellbeing and mental health outcomes during the COVID-19 pandemic, involving a representative sample of 121,066 adults.
- Researchers analyzed both modifiable (like coping strategies and pre-pandemic stress) and non-modifiable factors (such as age, gender, and socioeconomic status), finding significant negative effects on wellbeing and psychopathology scores during the pandemic.
- The study identified 15 modifiable and 9 non-modifiable risk factors, alongside 13 modifiable and 3 non-modifiable protective factors, emphasizing the importance of social support and coping strategies in mental health outcomes.
Technical considerations for isolated limb perfusion: A consensus paper.
Eur J Surg Oncol
June 2024
Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Background: Isolated limb perfusion (ILP) is a well-established surgical procedure for the administration of high dose chemotherapy to a limb for the treatment of advanced extremity malignancy. Although the technique of ILP was first described over 60 years ago, ILP is utilised in relatively few specialist centres, co-located with tertiary or quaternary cancer centres. The combination of high dose cytotoxic chemotherapy and the cytokine tumour necrosis factor alpha (TNFα), mandates leakage monitoring to prevent potentially serious systemic toxicity.
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