In compact photo-bioreactors with high concentration of micro organisms in cultural medium the zone volume of photoabsorption is essentially smaller then general working volume of the apparatus. This discrepancy is overcome by providing an intensive exchange between the dark and light zones. A quantitative characteristic of the intensity of migration exchange is introduced. It is the specific coefficient of mass transfer determined on the basis of solving the problem of Brown convective diffusion near the photoabsorption surface. The structural dependence of the quantity on the problem parameters is found. The qualitative and quantitative difference of this dependence near solid and free surface is discussed.
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Pharmacol Rep
January 2025
Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, 3004, Australia.
Background: Due to its availability and perceived safety, paracetamol is recommended even during pregnancy and for neonates. It is used frequently alone or in combination with other drugs required for the treatment of various chronic conditions. The aim of this study was to investigate potential effects of drug interactions on paracetamol metabolism and its placental transfer and entry into the developing brain.
View Article and Find Full Text PDFVaccines (Basel)
January 2025
Pharmaceutical Regulatory Affairs, Department of Pharmaceutical Industry, Graduate School, Chung-Ang University, Seoul 06974, Republic of Korea.
The emergence of more than 40 new infectious diseases since the 1980s has emerged as a serious global health concern, many of which are zoonotic. In response, many international organizations, including the US Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and the European Center for Disease Prevention and Control (ECDC), have developed strategies to combat these health threats. The need for rapid vaccine development has been highlighted by Coronavirus disease 2019 (COVID-19), and mRNA technology has shown promise as a platform.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
School of Chemical Sciences & Technology, School of Materials and Energy, Yunnan Provincial Center of Technology Innovation for New Materials and Equipment in Water Pollution Control, Institute of International Rivers and Eco-Security, Yunnan Province Engineering Research Center of Photocatalytic Treatment of Industrial Wastewater, Yunnan University, Kunming 650091, China.
Synthesis of the photocatalysts with near-infrared light response usually involves upconversion materials or plasmon-assisted noble metals. Herein, NiTiO/TiO was synthesized by using waste tobacco stem-silks as biotemplates and tetra-tert-butyl orthotitanate and nickel nitrate as precursors in a one-pot procedure. NiTiO(1.
View Article and Find Full Text PDFAnal Chem
January 2025
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
Urea is an important biomarker for diagnosing various kidney and liver disorders. However, many existing methods rely on invasive blood sampling, which can potentially harm patients. Saliva has been recently recognized as a noninvasive and easily collectible alternative to blood for urea quantification.
View Article and Find Full Text PDFMetabolites
January 2025
Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, Singapore 308433, Singapore.
: Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder characterized by intermittent upper airway obstruction, leading to significant health consequences. Traditional diagnostic methods, such as polysomnography, are time-consuming and resource-intensive. : This study explores the potential of proton-transfer-reaction mass spectrometry (PTR-MS) in identifying volatile organic compound (VOC) biomarkers for the non-invasive detection of OSA.
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