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Treatment modification after second-line failure among people living with HIV in the Asia-Pacific.
Antivir Ther
May 2022
The Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.
Background: The World Health Organization recommends continuation with the failing second-line regimen if third-line option is not available. We investigated treatment outcomes among people living with HIV in Asia who continued with failing second-line regimens compared with those who had treatment modifications after failure.
Methods: Treatment modification was defined as a change of two antiretrovirals, a drug class change or treatment interruption (TI), all for >14 days.
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