Dr. Michael Buonocore is known for his innovative research on the preparation of the enamel surface with a weak acid to enhance adhesion of an organic plastic chemical sealant and the polymerization in situ of a sealant with ultraviolet light. His co-workers at Eastman Dental Center aided and extended his research findings. The purpose of his original research was the development of a sealant to prevent occlusal caries on posterior teeth. However, the major impact of his work has been the development of adhesive restorative techniques. Although it has been demonstrated that (i) bacteria tend to die out and caries does not progress if early caries lesions are inadvertently sealed, (ii) sealant retention rates are favorable, and (iii) sealants are cost-effective, the use of sealants by the profession is still far short of early expectations.
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http://dx.doi.org/10.1177/00220345960750010401 | DOI Listing |
Magnetic resonance spectroscopy (MRS) provides unique information about the neurobiological substrates of brain function in health and disease. However, many of the physical principles underlying MRS are distinct from those underlying magnetic resonance imaging, and they may not be widely understood by neuroscientists new to this methodology. This review describes these physical principles and many of the technical methods in current use for MRS experiments.
View Article and Find Full Text PDFBrain Struct Funct
June 2016
Department of Psychiatry and Behavioral Sciences, The MIND Institute, University of California, Davis, 2825 50th Street, Sacramento, CA, 95817, USA.
We have longitudinally assessed normative brain growth patterns in naturalistically reared Macaca mulatta monkeys. Postnatal to early adulthood brain development in two cohorts of rhesus monkeys was analyzed using magnetic resonance imaging. Cohort A consisted of 24 rhesus monkeys (12 male, 12 female) and cohort B of 21 monkeys (11 male, 10 female).
View Article and Find Full Text PDFMol Autism
June 2015
The MIND Institute, School of Medicine, University of California at Davis, 2805 50th Street, Sacramento, 95817 California USA ; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California at Davis, Sacramento, 95817 California USA.
[This corrects the article DOI: 10.1186/s13229-015-0005-4.].
View Article and Find Full Text PDFMol Autism
May 2015
The MIND Institute, University of California at Davis, School of Medicine, 2805 50th Street, Sacramento, CA 95817 USA ; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California at Davis, Sacramento, CA 95817 USA.
Background: Abnormalities in the corpus callosum have been reported in individuals with autism spectrum disorder (ASD), but few studies have evaluated young children. Sex differences in callosal organization and diffusion characteristics have also not been evaluated fully in ASD.
Methods: Structural and diffusion-weighted images were acquired in 139 preschool-aged children with ASD (112 males/27 females) and 82 typically developing (TD) controls (53 males/29 females).
Psychiatry Res
April 2015
Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA; The MIND Institute, University of California, Davis, Sacramento, CA 95817, USA. Electronic address:
The fornix is the primary subcortical output fiber system of the hippocampal formation. In children with 22q11.2 deletion syndrome (22q11.
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