The Staphylococcus aureus pckA gene was identified and characterized. A pckA mutant lacked detectable phosphoenolpyruvate carboxykinase activity and grew poorly in the absence of glucose. Both enzymatic activity and pckA promoter activity in wild-type cells grown in the absence of glucose were at least 22-fold greater than activities in cells grown in the presence of glucose.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC178095PMC
http://dx.doi.org/10.1128/jb.178.11.3362-3364.1996DOI Listing

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