An efficacious method of cloning the sequences common for two cDNAs was proposed. The method was used for constructing a library of expressed sequences evolutionarily conserved for human and hamster.
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J Org Chem
January 2025
Department of Chemistry and Chemical Engineering, Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, Liaocheng University, Liaocheng 252059, China.
Multipalladium clusters possess peculiar structures and synergistic effects for reactivity and selectivity. Herein, -symmetric tripalladium clusters (, 0.5 mol %) afford C-regioselective SMCC of 2,4-dibromopyridine with phenylboronic acids or pinacol esters (C:C up to 98:1), in contrast to Pd(OAc) in ligand-free conditions.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
Department of Applied Chemistry and Institute of Natural Sciences, Kyung Hee University, Yongin-si 17104, Gyeonggi-do, Republic of Korea.
The combination of molybdenum disulfide (MoS) with plasmonic nanomaterials has opened up new possibilities in biological applications by combining MoS's biocompatibility and high surface area with the optical sensitivity of plasmonic metals. These MoS-plasmonic hybrid systems hold great promise in areas such as biosensing, bioimaging, and phototherapy, where their complementary properties facilitate improved detection, real-time visualization, and targeted therapeutic interventions. MoS's adjustable optical features, combined with the plasmon resonance of noble metals such as gold and silver, enhance signal amplification, enabling detailed imaging and selective photothermal or photodynamic therapies while minimizing effects on healthy tissue.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Chemical Engineering, University of Florida, Gainesville, FL 32611.
We describe a microfluidic device to extract DNA from a cell lysate, without the need for centrifuges, magnetic beads, or gels. Instead, separation is driven by transverse migration of DNA, which occurs when a polyelectrolyte solution flowing through a microfluidic channel is subjected to an electric field. The coupling of the weak shearing with the axial electric field is highly selective for long, flexible, charged molecules, of which DNA is the sole example in a typical cell lysate.
View Article and Find Full Text PDFMalar J
January 2025
West African Centre for Cell Biology of Infectious Pathogens, Accra University of Ghana, Volta Rd, Accra, Ghana.
Background: Malaria remains a leading cause of death worldwide, claiming over 600,000 lives each year. Over 90% of these deaths, mostly among children under 5 years, occur in sub-Saharan Africa and are caused by Plasmodium falciparum. The merozoites stage of the parasite, crucial for asexual development invade erythrocytes through ligand-receptor interactions.
View Article and Find Full Text PDFBMC Genomics
January 2025
School of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, 325035, China.
Background: Broussonetia papyrifera, B. monoica, and B. kaempferi belong to the genus Broussonetia (Moraceae).
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