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Alantolactone mitigates the elevation of blood pressure in mice induced by angiotensin II by inhibiting calcium channel activation.
BMC Cardiovasc Disord
January 2025
Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
Background: The dried root of Inula helenium L., known as Inulae Radix in Mongolian medicine, is a widely used heat-clearing plant drug within the Asteraceae family. Alantolactone (ATL), a compound derived from Inulae Radix, is a sesquiterpene lactone with a range of biological activities.
View Article and Find Full Text PDFDifferential physiological and yield responses of selected mung bean (Vigna radiata (L.) R. Wilczek) genotypes to various high-temperature stress regimes.
Sci Rep
January 2025
Feed the Future Innovation Lab for Collaborative Research on Sustainable Intensification, Kansas State University, Manhattan, KS, 66506, USA.
The increasing frequency of heat stress events due to climate change disrupts all stages of plant growth, significantly reducing yields, especially in crops like mung bean (Vigna radiata (L.) R. Wilczek).
View Article and Find Full Text PDFCooperative condensation of RNA-DIRECTED DNA METHYLATION 16 splicing isoforms enhances heat tolerance in Arabidopsis.
Nat Commun
January 2025
The National Engineering Laboratory of Crop Stress Resistance Breeding, School of Life Sciences, Anhui Agricultural University, Hefei, China.
Dissecting the mechanisms underlying heat tolerance is important for understanding how plants acclimate to heat stress. Here, we identify a heat-responsive gene in Arabidopsis thaliana, RNA-DIRECTED DNA METHYLATION 16 (RDM16), which encodes a pre-mRNA splicing factor. Knockout mutants of RDM16 are hypersensitive to heat stress, which is associated with impaired splicing of the mRNAs of 18 out of 20 HEAT SHOCK TRANSCRIPTION FACTOR (HSF) genes.
View Article and Find Full Text PDFEffects of thermopriming and bacteria-mediated heat-stress acclimation strategies on seed yield and quality criteria in Brassica napus cv Aviso and Camelina sativa cv Calena.
Planta
January 2025
Normandie Université, UNICAEN, INRAE, UMR 950 Ecophysiologie Végétale, Agronomie Et Nutritions N, C, S, Esplanade de La Paix CS14032, 14032, Caen Cedex 5, France.
The effects of intense heat during the reproductive phase of two Brassica species-B. napus and C. sativa-could be alleviated by a prior gradual increase exposure and/or PGPR inoculation.
View Article and Find Full Text PDFEvaluation of Three Viral Capsid Integrity qPCR Methods for Wastewater-Based Viral Surveillance.
Food Environ Virol
January 2025
School of Environmental and Natural Sciences, Bangor University, Bangor, Gwynedd, LL57 2UW, UK.
Capsid Integrity qPCR (CI-qPCR) assays offer a promising alternative to cell culture-based infectivity assays for assessing pathogenic human virus viability in wastewater. This study compared three CI-qPCR methods: two novel (Crosslinker, TruTiter) and one established (PMAxx dye). These methods were evaluated on heat-inactivated and non-heat-inactivated 'live' viruses spiked into phosphate-buffered saline (PBS) and wastewater, as well as on viruses naturally present in wastewater samples.
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