A structural change of chromosome 1 in q12 may be a new, possibly consistent, chromosome change in adenocarcinoma of the prostate.

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http://dx.doi.org/10.1016/0165-4608(95)00213-8DOI Listing

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Deletion (1)(q12) and double minutes in a metastatic adenocarcinoma of the prostate.

Cancer Genet Cytogenet

January 2000

Departmento de Biologia, Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto, Brazil.

Cytogenetic analysis after short-term cultures were performed on an invasive and moderately-differentiated prostatic adenocarcinoma. The results showed a normal male chromosomal complement in most metaphases examined. Furthermore, several abnormalities were found, including del(1)(q12), double minute and ring chromosomes, acentric fragments, triradial figures, and near-tetraploid cells.

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A structural change of chromosome 1 in q12 may be a new, possibly consistent, chromosome change in adenocarcinoma of the prostate.

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