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Skin, Heart, and CNS Involvement in Granulomatosis With Polyangiitis: A Case Report.
Cureus
August 2024
Nephrology, Ascension Via Christi St. Francis Hospital, Wichita, USA.
We discuss the case of a 60-year-old male who presented with ankle pain, a necrotic rash, and progressive weakness in both lower limbs and the right upper limb. An infectious workup of the skin lesions came back negative. Additionally, his kidney function tests indicated an acute kidney injury.
View Article and Find Full Text PDFExploring the Complexities of Non-Bacterial Thrombotic Endocarditis: Highlights from Literature and Case Studies.
J Clin Med
August 2024
Department of Clinical and Experimental Medicine, G. Martino University Hospital, Cardiology Unit, 98122 Messina, Italy.
Non-bacterial thrombotic endocarditis (NBTE) is a form of non-infective endocarditis characterized by the deposition of sterile fibrin and platelets on cardiac valves. Even though some studies have identified important pathophysiological features, many aspects remain poorly understood. Given its wide availability, transthoracic echocardiography is typically the initial diagnostic approach to the patient.
View Article and Find Full Text PDFContemporary Role of Positron Emission Tomography (PET) in Endocarditis: A Narrative Review.
J Clin Med
July 2024
Institute of Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.
Endocarditis, a serious infectious disease, remains a diagnostic challenge in contemporary clinical practice. The advent of advanced imaging modalities has contributed significantly to the improved understanding and management of this complex disease. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) imaging has shown remarkable potential in improving the diagnostic accuracy of endocarditis.
View Article and Find Full Text PDFTrivalvular nonbacterial thrombotic endocarditis in a patient with colon adenocarcinoma: a case report.
J Med Case Rep
August 2023
Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Background: Nonbacterial thrombotic endocarditis is a rare complication of prothrombotic states such as neoplasms that can cause valvular dysfunction and life-threatening complications. Nonbacterial thrombotic endocarditis usually affects the left-sided valves; however, only a minority of cases involving the tricuspid valve have been reported in medical literature.
Case Presentation: The current report describes trivalvular involvement by nonbacterial thrombotic endocarditis in a 54-year-old Azeri female patient with metastatic colorectal carcinoma.
16S rRNA Gene PCR/Sequencing of Heart Valves for Diagnosis of Infective Endocarditis in Routine Clinical Practice.
J Clin Microbiol
August 2023
Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Sequencing is increasingly used for infective endocarditis (IE) diagnosis. Here, the performance of 16S rRNA gene PCR/sequencing of heart valves utilized in routine clinical practice was compared with conventional IE diagnostics. Subjects whose heart valves were sent to the clinical microbiology laboratory for 16S rRNA gene PCR/sequencing from August 2020 through February 2022 were studied.
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