This study demonstrates that CD8+ cytotoxic lymphocytes (CTL) are found in both primary and secondary syphilis lesions. CD8+ T cells were detected by immunohistology, and mRNAs for granzyme B and perforin were detected by reverse transcription and PCR, suggesting that CD8+ cytotoxic lymphocytes are activated.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC173879 | PMC |
| http://dx.doi.org/10.1128/iai.64.3.1048-1050.1996 | DOI Listing |
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