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An evidence-based update on the diagnosis and management of irritable bowel syndrome.
Expert Rev Gastroenterol Hepatol
January 2025
Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.
Introduction: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction affecting 5% of the population. The cardinal symptoms are abdominal pain and altered stool form or frequency.
Areas Covered: Diagnosis and management of IBS.
Objectives: The objective of this study was to identify factors associated with in-hospital deaths of newborns admitted to a special care newborn unit (SCANU) in southern Bangladesh.
Design: Retrospective cohort.
Setting: SCANU of Patuakhali Medical College Hospital, Patuakhali, Bangladesh.
Exploration of Cytokines and Microbiome Among Males and Females with Diarrhea-Predominant Irritable Bowel Syndrome.
Dig Dis Sci
January 2025
School of Nursing, University of Washington, Seattle, WA, USA.
Background: Whether pathophysiological factors differ between males and females with irritable bowel syndrome-diarrhea (IBS-D) remains to be tested. To better understand potential sex differences, males with IBS-D were compared to naturally cycling females and to females with IBS-D taking hormonal contraception on plasma levels of cytokines and gut microbiome characteristics.
Methods: Males and females with Rome III IBS-D completed questionnaires and kept a daily symptom diary for 28 days.
The Impact of , , and in Diarrheal Infections in Central Africa (1998-2022): A Systematic Review.
Int J Environ Res Public Health
December 2024
Bacteriology Laboratory, Medical Analysis Research Unit, Interdisciplinary Center for Medical Research of Franceville (CIRMF), Franceville BP 769, Gabon.
Background: Gastric diseases caused, in particular, by , non-typhoidal , and resulting from food and/or water problems, are a disproportionately distributed burden in developing countries in Central Africa. The aim of this work was to compile a list of studies establishing the prevalence of the involvement of these bacterial genera in diarrheal syndromes in Central Africa from 1998 to 2022.
Methods: The Preferred Reporting Articles for Systemic Reviews and Meta-Analyses, six (6) database (Pubmed, Google Scholar, Semantic Scholar, Freefullpdf, and Scinapse) were perused for research on the role of , and diarrheal infections in humans and animals, in 9 country of Central Africa over from 1998 to 2022.
Leveraging human microbiomes for disease prediction and treatment.
Trends Pharmacol Sci
January 2025
Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, TX, USA. Electronic address:
The human microbiome consists of diverse microorganisms that inhabit various body sites. As these microbes are increasingly recognized as key determinants of health, there is significant interest in leveraging individual microbiome profiles for early disease detection, prevention, and drug efficacy prediction. However, the complexity of microbiome data, coupled with conflicting study outcomes, has hindered its integration into clinical practice.
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