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Protective effects of against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet.

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Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Background: Fatty Liver Disease (FLD) progresses from steatosis to steatohepatitis and, if left untreated, can lead to irreversible conditions such as cirrhosis and hepatocarcinoma. The etiology of FLD remains unclear, but factors such as overconsumption, poor diet, obesity, and diabetes contribute to its development. Palmitic acid (PA) plays a significant role in FLD progression by inducing apoptosis, inflammation, oxidative stress, and endoplasmic reticulum (ER) stress in hepatocytes.

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Purpose: Grit, or a person's "perseverance and passion for long-term goals," is a noted character trait for success. This qualitative descriptive study explored the experiences and challenges faced by nursing students, focusing on how these experiences shaped their educational journeys and exploring the role of perseverance and passion in nursing education and its potential for student success in a nursing education program.

Methods: Purposive sampling was utilized to select study participants from higher education institutions in Southeastern Pennsylvania.

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Terrestrial nanoparticles and geospatial optics: Implications for environmental impact from anthropogenic contaminants in the Caribbean region.

Sci Total Environ

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Centre of Molecular and Environmental Biology (CBMA), Aquatic Research Network (ARNET) Associate Laboratory, Department of Biology, University of Minho, 4710-057 Braga, Portugal; Institute of Science and Innovation for Bio-Sustainability (IB-S), University of Minho, 4710-057 Braga, Portugal.

Atmospheric contaminants from natural processes and anthropogenic activities pose a major problem to the environment. Here we analyze the dynamics of atmospheric and terrestrial contaminant concentrations in sediments containing chemical elements, such as nanoparticles (NPs) and ultrafine particles in hydrological sources of the Caribbean region of Colombia. Terrestrial sediments were collected from 2022 to 2024, and quantified for major chemical elements in the form of NPs and ultrafine particles in runoff receiving areas along the banks of Colombia's Ciénaga Grande in Santa Marta Bay, on the Isla de Salamanca.

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