FRD, a nuclear and dominant spontaneous mutant of Saccharomyces cerevisiae capable of growing in up to 2 M NaCl, was isolated. Compared with parental cells, the mutant cells have a lower intracellular Na+/K+ ratio, shorter generation times in the presence of 1 M NaCl, and alterations in gene expression.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC178038 | PMC |
http://dx.doi.org/10.1128/jb.178.10.2978-2981.1996 | DOI Listing |
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