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Article Synopsis
  • * A case study involved a 59-year-old male with non-ischemic cardiomyopathy, admitted for acute congestive heart failure, where severe left ventricular dysfunction was confirmed through echocardiogram findings, including blood flow variations known as Doppler alternans.
  • * The echocardiographic detection of these variations occurred before any clinical symptoms, highlighting the importance of echocardiography for assessing heart function and guiding timely medical intervention.
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Background And Aims: Neurovascular ultrasound (nvUS) of the epiaortic arteries is an integral part of the etiologic workup in patients with ischemic stroke. Aortic valve disease shares similar vascular risk profiles and therefore not only presents a common comorbidity, but also an etiologic entity. The aim of this study is to investigate the predictive value of specific Doppler curve flow characteristics in epiaortic arteries and the presence of aortic valve disease.

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Influence of left ventricular systolic dysfunction on occurrence of pulsus tardus in patients with aortic stenosis.

J Cardiol

October 2021

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Background: Although the time difference between peak of left ventricular (LV) and aortic systolic pressures (T), which is considered to in part reflect pulsus tardus, is reported to be associated with clinical outcome in aortic stenosis (AS), its physiological determinants remain to be elucidated. We hypothesized that not only AS severity but also LV systolic dysfunction could be associated with occurrence of pulsus tardus.

Methods: T was measured by simultaneous LV and aortic pressure tracing in 74 AS patients and prolonged T was defined as ≥66 ms according to the previous report.

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• Pulsus alternans is characterized by beat-to-beat variability in cardiac contractile strength. • Besides severe LV failure, hypovolemia and tachycardia can provoke pulsus alternans. • Right ventricular or biventricular alternans is reported only sporadically in people.

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Objectives: To characterize fluctuations in peak systolic velocities (PSVs) in Doppler waveforms of the carotid artery in patients with and without obstructive airway disease and in volunteers subjected to incremental levels of airway resistance in an experimental model.

Methods: The PSV variation in common carotid waveforms was measured in 100 patients who had had a carotid ultrasound examination and no respiratory or carotid disease. This was compared to that of patients who had this study during an admission for acute exacerbation of chronic obstructive pulmonary disease (COPD).

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