AI Article Synopsis

  • The study explores how magnetic resonance angiograms (MRAs) can show reduced signal intensity in blood vessels, potentially resembling blood clots.
  • Researchers conducted simulations and tests to observe the signal changes in MRAs, particularly behind sharp curves in blood vessel shapes.
  • Findings revealed that the signal loss in the center of vessels is due to flow dynamics and can be minimized by adjusting imaging techniques, leading to more accurate interpretations of MRAs.

Article Abstract

Purpose: To investigate the appearance of reduced signal intensity in the center of blood vessels on magnetic resonance (MR) angiograms that can mimic intraluminal thrombus.

Materials And Methods: Simulations and phantom studies were performed to analyze MR angiogram appearance distal to a pronounced curve.

Results: Saturation effects substantially lower the signal strength in the center of the vessel relative to that at the vessel periphery. These effects appeared even though the flow was well ordered and laminar. In curved geometries, secondary flow patterns produced counter-rotating vortices, which moved the fastest-moving particles to the outside of the curve and folded the slow-moving particles to the center of the vessel.

Conclusion: Imaging parameter choices that reduce saturation, such as acquisition of a two-dimensional section transverse to the vessel and through the questionable region, effectively eliminate the central hypointensity effect in vivo.

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Source
http://dx.doi.org/10.1148/radiology.198.3.8628862DOI Listing

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