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Surgical treatment of craniofacial cleft and orbital hypertelorism: a single-center cohort study.

Neurosurg Focus

January 2025

3ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Objective: Craniofacial clefts, characterized by congenital disruptions in the development of facial and cranial tissues, often present alongside orbital hypertelorism (ORH), an abnormal increase in the interorbital distance. These conditions pose significant challenges in craniofacial surgery due to the complex anatomical and functional considerations involved. This single-center cohort study retrospectively analyzed 22 patients diagnosed with craniofacial cleft syndromes and ORH who were treated at the Craniofacial Centre, Fatima Plastic and Reconstructive Surgery Hospital between July 2016 and October 2023.

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Article Synopsis
  • The study investigates the effectiveness of a surgical procedure (extended strip craniectomy with bilateral barrel staving) for treating isolated craniosynostosis of the sagittal suture in infants, specifically focusing on its impact on cranial shape without directly addressing forehead issues.
  • Results showed significant improvements in aspects like bossing angle and cephalic index over a year, although the cranial shape did not entirely match that of healthy peers, indicating partial normalization but not complete correction.
  • The research validates 3D photogrammetry as a useful noninvasive tool for assessing cranial changes post-surgery, suggesting potential for wider clinical applications in monitoring cranial morphology.
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Objective: Sagittal synostosis is the most common type of craniosynostosis, resulting in deformity with distinctive morphological characteristics. These include occipital narrowing, parietal narrowing, anteriorly shifted vertex with parietal depression, and exaggerated frontal bossing. The traditional cephalic index affords limited reliability in quantifying initial severity and correction.

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Objective: This study reports the authors' experience with surgical interventions for nonsyndromic craniosynostosis. They assessed open surgery and minimally invasive endoscopic suturectomy in terms of periprocedural outcomes and related risk factors for postoperative complications and reoperation. This study aimed to provide insights toward surgical approach decisions and lay the groundwork for future prospective studies in this field.

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Craniosynostosis limits normal cranial growth, significantly affecting the growth and development of children. This increase in intracranial pressure results in significant cosmetic and functional losses. This study investigated the efficacy of combining molding helmets with suturectomy for craniosynostosis.

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