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Mod Pathol
January 2025
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; Computational Pathology and AI Center of Excellence (CPACE), University of Pittsburgh, Pittsburgh, PA. Electronic address:
Artificial Intelligence (AI) and Machine Learning (ML) are transforming the field of medicine. Healthcare organizations are now starting to establish management strategies for integrating such platforms (AI-ML toolsets) which leverage the computational power of advanced algorithms to analyze data and to provide better insights which ultimately translates to enhanced clinical decision-making and improved patient outcomes. Emerging AI-ML platforms and trends in pathology and medicine are reshaping the field by offering innovative solutions to enhance diagnostic accuracy, operational workflows, clinical decision support, and clinical outcomes.
View Article and Find Full Text PDFLife Sci
January 2025
Hubei Key Laboratory of Nanomedicine for Neurodegenerative Diseases, School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China; Department of Pharmacology, Hubei University of Medicine, Shiyan 440070, China; Beijing Tiantan Hospital, Capital Medical University, Beijing 10070, China; China National Clinical Research Center for Neurological Diseases, Beijing 10070, China; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 10070, China. Electronic address:
The global increase in obesity-related metabolic disorders has led to metabolic dysfunction-associated steatotic liver disease (MASLD) emerging as one of the most prevalent chronic liver disease worldwide. Despite growing concerns, the exact pathogenesis of MASLD remains unclear and no definitive treatments have been made available. Consequently, the need for comprehensive research on MASLD is more critical than ever.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Background: Physiotherapy has emerged as an important health strategy to deliver lifestyle, exercise and physical activity for people with knee osteoarthritis. However, little is known about the extent to which physiotherapists adhere to clinical practice guidelines. This study aimed to explore the perspectives and care patterns of physiotherapists in Sydney, Australia on their delivery of knee osteoarthritis care and how this aligns with the 2019 Osteoarthritis Research Society International (OARSI) guidelines.
View Article and Find Full Text PDFLearn Behav
January 2025
Normandie UnivUnicaen, CNRS, EthoS, 14000, Caen, France.
Episodic memory and future thinking are generally considered as two parts of the same mental time travelling system in vertebrates. Modern cephalopods, with their independent evolutionary lineage and their complex cognitive abilities, appear as promising species to determine whether these abilities have separate evolutionary histories or not. In our study, we tested future-planning abilities in a cephalopod species which has been shown to possess episodic-like memory abilities: the common cuttlefish.
View Article and Find Full Text PDFInflamm Res
January 2025
Departments of Oral Medicine, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong Province, China.
Mucosal-associated invariant T (MAIT) cells, a type of T lymphocytes with innate-like characteristics, are crucial in bridging innate and adaptive immunity. When activated, MAIT cells release various inflammatory molecules and swiftly respond to antigens. Notably, numerous studies highlight the significant impact of MAIT cells on tumors and various immune disorders by influencing the immune microenvironment.
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