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Molecular surveillance of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Mozambique, 2023.
Malar J
December 2024
Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
Background: Rapid diagnostic tests (RDTs) based on the detection of Plasmodium falciparum histidine rich protein 2 (PfHRP2) are widely used for the diagnostic of P. falciparum in Africa. However, deletions of the pfhrp2 and pfhrp3 genes can lead to false negative test results and compromise appropriate case management.
View Article and Find Full Text PDFHIV Self-Testing: A Discussion on the Benefits, Limitations, and Implications for Public Health with a Focus on Poland.
Diagnostics (Basel)
November 2024
Department of Infectious Diseases, Liver Disease and Acquired Immune Deficiencies, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Background/objectives: A late HIV diagnosis represents a significant public health concern in Poland, with approximately 50% of patients being identified as late presenters (LPs), resulting in the delayed initiation of treatment. This study assesses the potential of HIV self-testing (HIVST) to enhance early detection, particularly among heterosexual individuals, and evaluates its advantages and limitations within the Polish context.
Methods: This study examines the advantages and disadvantages of HIVST by analyzing data from various studies.
Diagnostic accuracy of active pulmonary tuberculosis screening during detention admission: a systematic review.
J Med Life
July 2024
Department of Global Health, Euclid University, Bangui, Central African Republic.
Article Synopsis
- * A systematic review aimed to evaluate the diagnostic accuracy of TB screening tests for individuals upon detention admission, but no studies met the inclusion criteria despite screening over 2,400 records.
- * The review highlights the need for more comprehensive data on TB screening methods in detention settings and suggests that global TB initiatives should conduct multi-site studies for better insights.
Late Relapse of Previous Pulmonary Cryptococcosis With Symptoms Resembling Cerebral Infarction: A Case Report.
Case Rep Infect Dis
October 2024
Department of Neurosurgery, Otto-Von-Guericke-University Magdeburg, Magdeburg, Germany.
Cryptococcosis, an infection caused by , predominantly targets the central nervous system (CNS) in patients with AIDS but is not limited to this group. The disease can also occur in individuals with various immunosuppressive conditions, frequently involving the brain or lungs. Cryptococcal meningitis (CM) is the most common form of fungal meningoencephalitis, leading to intracerebral infections, cerebral infarction, or hydrocephalus.
View Article and Find Full Text PDFPAP Test Versus Colposcopy for Cervical Cancer Screening in HIV-Seropositive Women: A Case-Control Study.
J Obstet Gynaecol India
August 2024
Pathology, Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital, New Delhi, India.
Purpose: The prevalence of pre-invasive lesions (PIL) of cervix in human immunodeficiency virus (HIV)-seropositive women ranges from 12.5 to 69%. Although Papanicolaou (PAP) test is the recommended screening method, it has concerns owing to high false-negative cytology in HIV-infected women and is associated with high attrition rates.
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